Κατεύθυνση Παθολογία της Κύησης
Library of the School of Health Sciences

2021-01-17

2021

Lampropoulou Dionysia

Μαστοράκος Γεώργιος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Καλανταρίδου Σοφία, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Σαλάκος Νικόλαος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ

FGR και μεταβολικό σύνδρομο, πρώιμη αδρεναρχή, πρώιμη ήβη και πολυκυστικές ωοθήκες

Greek

FGR and metabolic syndrome, early adrenarch, precocious puberty and PCOS

Introduction: Metabolic syndrome is still a set of metabolic disorders that leads to the development of Type II Diabetes and cardiovascular disease. Key representatives are obesity, dyslipidemia, hypertension and diabetes mellitus. This syndrome remains a center of research as it consitutes an important cause of morbidity and mortality. A number of diseases and metabolic disorders appear to be related to metabolic syndrome. We note in particular the fatty liver, sleep apnea syndrome and polycystic ovary syndrome that are currently documented to be associated with metabolic syndrome and insulin resistance. Modern lifestyles, dietary changes and reduced physical activity favor obesity and thus the development of metabolic syndrome.

Purpose: The purpose of the present study is literature review and association of embryos with intrauterine growth restriction with metabolic syndrome and a cascade of hormonal disorders in adolescence.

Results: Intrauterine growth restriction appears to be related to a set of metabolic and endocrinological disorders. Of relevance is the relationship between intrauterine growth restriction and premature adrenarche, precocious puberty, polycystic ovarian syndrome and metabolic syndrome. There is possibly a common pathophysiologic mechanism connecting these entities.

Conclusion: Endometrial growth restriction has been associated with an increased risk of metabolic syndrome, premature adrenarche, precocious puberty, polycystic ovary syndrome, and a range of psychological effects of these entities on adolescents. The challenge is to change the modern way of life in order to reduce morbidity and mortality.

Health Sciences

FGR, Metabolic syndrome, Early adrenarch, Precocious puberty, PCOS

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Yes

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https://pergamos.lib.uoa.gr/uoa/dl/object/2932548