Unit:
Κατεύθυνση ΒιοστατιστικήLibrary of the School of Health Sciences
Author:
Tsiogka Anastasia
Supervisors info:
Σαμόλη Ευαγγελία, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Καρμίρης Ευθύμιος, Επιμελητής, Οφθαλμολογική Κλινική, 251 ΓΝΑ
Spaeth George, Professor, Department of ophthalmlogy, Wills Eye Institute
Original Title:
An epidemiological study evaluating contrast sensitivity change in refractive surgery
Translated title:
An epidemiological study evaluating contrast sensitivity change in refractive surgery
Summary:
Purpose: To assess contrast sensitivity of central and peripheral vision with a newly developed internet-based Spaeth/Richman Contrast Sensitivity (SPARCS) test in subjects who underwent refractive surgery (PRK and femto-LASIK) for myopia in comparison to matched controls.
Methods: In this retrospective cross-sectional study, subjects who underwent a refractive surgery and normal controls were evaluated using the SPARCS. Contrast sensitivity testing was performed in each eye in a standardized testing environment in randomized order. SPARCS scores were obtained for central and 4 peripheral areas (right upper (RUQ), right lower (RLQ), left upper (LUQ), and left lower quadrants (LLQ)) and a new variable “peripheral” was created, which was the sum of 4 peripheral scores. Total, central and peripheral SPARCS scores in subjects with refractive surgery were compared with controls controlling for confounders (age, gender, changed diopters, smoking). Univariate linear regression, multivariate linear regression and mixed linear regression were used for our analysis.
Results: A total of 186 eyes from 93 subjects were analyzed: 62 eyes from 31 subjects at each group respectively. The PRK group had a lower total score of 5.9 points (p-value <0.001), a lower central score of 1.6 points (p-value =0.018) and a lower peripheral score of 5.5 points (p-value =0.006) than control group, but there was no statistically significant reduction in central and peripheral contrast sensitivity after LASIK compared to control group.
Conclusions: SPARCS offers the advantage of determining contrast sensitivity peripherally and centrally to patients that underwent a myopic refractive surgery. There was a statistically significant reduction in central and peripheral contrast sensitivity after PRK, but there was no statistically significant reduction in central and peripheral contrast sensitivity after femto-LASIK.
Main subject category:
Health Sciences
Keywords:
Contrast sensitivity, Refractive surgery, LASIK, PRK
