Κατεύθυνση Διασυνδετική Ψυχιατρική και Απαρτιωμένη Φροντίδα Σωματικής και Ψυχικής ΥγείαςLibrary of the School of Health Sciences
Ρωσσέτος Γουρνέλλης ,Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Δουζένης Αθανάσιος , Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Παρίσης Ιωάννης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Αγχώδεις και καταθλιπτικές εκδηλώσεις σε ασθενείς με καρδιακή ανεπάρκεια
Anxiety and depressive symptoms in petients with heart failure
Introduction: Heart failure, a chronic disease, which affects a significant part of the general population and has a large social-economic burden, has been linked to anxiety and depression disorders. The purpose of this study was to assess adherence to medication in patients with heart failure, to investigate depressive and stressful symptoms in patient with heart failure and to compare them with healthy controls, as well as to investigate their possible association with the duration of the disease.
Method: 40 patients with heart failure and 40 healthy controls participated in the study. Anxiety and depressive symptoms were evaluated by Hospital Anxiety and Depression Scale (HADS), while medication adherence was assessed by the Morisky Medication Adherence Scale (MMAS-8).
Result: The sample consisted of 56.3% men, with a mean age of 60.84 ± 14.85 years and 43.8% women with a mean age of 55.6 ± 18.13 years of age. The average duration of the disease was 6.68 ± 5.69 years for men and 7.13 ±
8.14 years for women. Women had significantly more severe heart failure with preserved ejection fraction and experienced significantly higher levels of anxiety than men. According to MMAS-8, 62.5% of patients presented high adherence to medication, while a 32.5% showed low adherence. A positive association of depressive symptoms with adherence to medication was observed. Patients had statistically significantly higher levels of depressive symptomatology than healthy
controls. There was no statistically significant difference in the occurrence of anxiety symptomatology between patients and healthy controls. A negative association between anxiety and depressive symptoms and the duration of the disease was observed, as well as a negative association between the duration of the disease and medication adherence.
Conclusions: In conclusion patients with heart failure present higher levels of depression compared to healthy controls, while no difference is observed with regard to depression. There is also a negative association of the duration of the disease with anxiety and depressive symptoms, as well as with adherence to medication. Future studies should further investigate the casual relationships between them, but also to provide useful knowledge for clinical practice
Main subject category:
Anxiety, Depression, Medication compliance, Heart failure, HADS, MMAS