Unit:
Κατεύθυνση Σύγχρονη διαγνωστική στη Δερματολογία και την ΑλλεργιολογίαLibrary of the School of Health Sciences
Author:
Dermitzaki Ioanna
Supervisors info:
Γρηγορίου Σταμάτιος, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Κατούλης Αλέξανδρος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Ρηγόπουλος Δημήτριος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Ευαισθητοποίηση ασθενών με αλλεργική δερματίτιδα εξ επαφής σε κοσμητολογικά προϊόντα
Translated title:
Sensitization in patients with allergic contact dermatitis to cosmetic products
Summary:
Objective: Contact Dermatitis (CD) is considered as a principal cause for almost half of the occupational disorders. CD is an inflammatory dermatosis triggered by allergens and irritant factors. The main two types of CD are: Irritant Contact Dermatitis (ICD), responsible for about 80% of all the Contact Dermatitis cases and Allergic Contact Dermatitis (ACD), a delayed, type IV, hypersensitivity reaction due to contact allergens.
The aim of this study was to identify the most common contact allergens in cosmetics ingredients in patients with allergic contact dermatitis, to focus on clinically relevant immune functions in order to understand the pathogenesis mechanisms, context and role of inflammation, as well as, the process of detecting the specific substances that cause allergic inflammation of a patient's skin, with Patch Tests.
Patients and methods: We conducted a retrospective search in the archives of the Patch Testing Laboratory of the “Andreas Syngros” Venereal & Dermatological Diseases Hospital of Athens. All patients with contact dermatitis and appropriate history between January 2017 and December 2018 were tested with the Standard European series and an extended cosmetic series.
Results: Three hundred and twenty six patients with allergic contact dermatitis were patch tested and 237 of them had at least one sensitization. The most common site involved were the periorbital area in 44% of the patients. Most frequent sensitizations identified were to nickel sulfate 37.73%, Fragrance mix I 14,11% and Myroxylon Pereira 12.27% in the European standard series and Cocamidopropylbetaine 6.13%, Propolis 3.37% and Τosylamide formaldehyde resin 1.53% in our extended cosmetic series.
Conclusions: We advise appropriate consultation for the patients in both treatment and prevention of allergic contact dermatitis due to cosmetics.
Main subject category:
Health Sciences
Keywords:
Cosmetics, Patch test, Cocamidopropyl betaine, Propolis, Nickel sulphate
