Third, fourth, sixth cranial nerve palsies, a systematic review

Postgraduate Thesis uoadl:2948080 113 Read counter

Unit:
Specialty Applied Neuroanatomy
Library of the School of Health Sciences
Deposit date:
2021-07-08
Year:
2021
Author:
Christodoulaki Eirini-Christina
Supervisors info:
Γεώργιος Στράντζαλης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Κωνσταντίνος Νάτσης, Καθηγητής, Ιατρική Σχολή, ΑΠΘ
Μαρία Πιάγκου, Επίκουρη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Third, fourth, sixth cranial nerve palsies, a systematic review
Languages:
English
Translated title:
Third, fourth, sixth cranial nerve palsies, a systematic review
Summary:
Introduction
Oculomotor nerve (CN III third cranial nerve), trochlear nerve (CNIV fourth cranial
nerve And abducens (CN VI sixth cranial nerve) constitute the ocular motor cranial
nerves.Ocular motor nerve palsies are commonly encountered and they can be either
congenital or acquired. Causes and underlying pathology of ocular motor nerve
palsies are variable and include vascular problems, tumors , infections and trauma.
Diagnosis is mainly based on clinical presentation. However, further investigation
may be necessary in order to find the cause and the appropriate treatment.
Aim
The aim of this study is to identify the causes of palsy of each of the ocular motor
neurons in order of frequency, according to the systematic review which was carried
out.
Material and methods
Searches were conducted in Pubmed to identify clinical studies on oculomotor,
trochlear and abducens nerve palsy. 56 studies satisfying inclusion criteria were
incorporated in the present analysis. Their findings are categorized on the basis of
underlying causes.
Results
Among 57 studies which were analyzed, 23 studies refer to the oculomotor nerve,7
(CN ΙII), 7 refer to the trochlear nerve and 26 refer to the abducens nerve. 10 of these
studies refer to all three ocular motor cranial nerves.
Conclusions
Among the ocular motor nerve palsies, abducens nerve palsy was found to be the
most common, followed by the oculomotor nerve palsy and finally the trochlear
nerve. Causes and underlying pathology of each of ocular motor nerve palsies vary.
The most common cause for oculomotor nerve palsy was vascular causes especially
in diabetics and aneurysm patients. In trochlear nerve palsy the most common cause
was trauma and congenital causes and for the abducens nerve the most common
cause was ischemia due to vascular causes and tumors. Prompt diagnosis and
treatment are essential.
Main subject category:
Health Sciences
Keywords:
Oculomotor nerve, Trochlear nerve, Abducens nerve, Palsy, Ocular motor nerve palsies
Index:
No
Number of index pages:
0
Contains images:
No
Number of references:
83
Number of pages:
60
File:
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