Short-term effects of manual therapy techniques on pain, disability and oxidative stress (LOOH) levels in patients with chronic mechanical neck pain

Postgraduate Thesis uoadl:2960440 7 Read counter

Unit:
Κατεύθυνση Εργαστηριακή / Βασική Έρευνα
Library of the School of Health Sciences
Deposit date:
2021-09-10
Year:
2021
Author:
Betsos Theodoros
Supervisors info:
Κουτσιλιέρης Μιχαήλ, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Φιλίππου Αναστάσιος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Χατζηγεωργίου Αντώνης, Επίκουρος Καθηγητής, Ιατρική Σχολή ΕΚΠΑ
Original Title:
Βραχυπρόθεσμη επίδραση τεχνικών Χειροθεραπείας (Manual Therapy) στην κλινική εικόνα και στα επίπεδα του οξειδωτικού στρες σε ασθενείς με χρόνιο αυχενικό μηχανικό πόνο
Languages:
Greek
Translated title:
Short-term effects of manual therapy techniques on pain, disability and oxidative stress (LOOH) levels in patients with chronic mechanical neck pain
Summary:
INTRODUCTION: Chronic mechanical neck pain can be caused by several factors, one of which is oxidative stress, while it has been shown that Manual Therapy is one of the most effective ways to treat this type of pain. The present study aimed to investigate the effect of Manual Therapy techniques on chronic mechanical neck pain and oxidative stress in patients with chronic mechanical neck pain.
METHODOLOGY: The study was performed on patients suffering from chronic mechanical neck pain. Thirty two volunteer patients were divided into 3 groups: 11 were the intervention group and were treated with Manual Therapy, 11 were the placebo group and received SHAM manual therapy and 10 formed another healthy control group that did not receive any treatment. Blood samples were taken from the intervention, placebo and healthy groups in three different conditions: a) before the start of a Manual Therapy (or placebo) session, b) after its completion and c) after the end of the last (ninth) treatment session. The study lasted three weeks and consisted of nine sessions. The dependent variables of the study were pain, lipid hydroperoxide (LOOH) levels as an indicator of oxidative stress, and functional ability of patients, which were evaluated at the above three time points, before and after the intervention.
RESULTS: A decrease in serum LOOH levels was observed in patients after the completion of the first session of Manual Therapy, while a further decrease was observed after the end of the last treatment session. Patients that received placebo treatment exhibited a smaller reduction in LOOH compared with the intervention group, the reduction of which remained steady after the ninth treatment session.
CONCLUSION: Patients with chronic mechanical neck pain showed an improvement in their clinical symptoms, both in terms of pain and functional ability, after treatment with Manual Therapy techniques. These findings suggest that Manual Therapy may be an effective method of treating chronic mechanical neck pain and reducing oxidative stress in those patients.
Main subject category:
Health Sciences
Keywords:
Manual Therapy, Manipulative therapy, Physiotherapy, Oxidative stress, Lipid peroxidation, Lipid hydroperoxide (LOOH)
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
67
Number of pages:
67

Βραχυπρόθεσμη επίδραση τεχνικών Χειροθεραπεί (Manual Therapy) final.pdf
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