Supervisors info:
Νικολέττα Ιακωβίδου, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Θεόδωρος Ξάνθος, Καθηγητής, Ιατρική Σχολή, Πανεπιστήμιο Κύπρου
Κωνσταντίνος Εκμεκτζόγλου,MD PhD
Summary:
BACK ROUND.Lung cancer is directly and causally related to smoking. Exposure of workers to inhaled substances in their working place, is an aggravating factor. The question of the study is, whether occupational exposure in conjunction with smoking results in earlier lung cancer and respiratory failure than when occupational absenteeism is absent.
METHODS.In the pulmonology clinic of the hospital “Agioi Anargyroi”, a study was carried out to observe successive patients with primary lung cancer, who are also smokers. The duration of the study was from February 1, 2018 to May 31, 2020. We divided the population into two groups. The first group, consists of patients with primary lung cancer who are also smokers that have been exposed to occupational exposure for at least 10 years, while the second group, lacks the occupational exposure factor.
RESULTS.The average age of onset of lung cancer in patients was statistically, significantly lower in occupationally exposed patients, than in non-occupationally exposed patients. More specifically, the average age of onset of lung cancer in occupationally exposed patients, was 65.5 years and the average age of onset of lung cancer in non-occupationally exposed patients, was 72.6 years. In addition, the average age of onset of respiratory failure, was statistically, significantly lower in occupationally exposed patients, than in non-occupationally exposed patients. More specifically, the average age of onset of respiratory failure in occupationally exposed patients, was 65.9 years and the average age of onset of respiratory failure in non-occupationally exposed patients, was 73.7 years.
CONCLUSION: It seems that exposure of smokers to inhaled substances in their working environment, leads to earlier lung cancer and respiratory failure, compared to the non-exposed workers.
ABSTRACT
BACK ROUND.Lung cancer is directly and causally related to smoking. Exposure of workers to inhaled substances in their working place, is an aggravating factor. The question of the study is, whether occupational exposure in conjunction with smoking results in earlier lung cancer and respiratory failure than when occupational absenteeism is absent.
METHODS.In the pulmonology clinic of the hospital “Agioi Anargyroi”, a study was carried out to observe successive patients with primary lung cancer, who are also smokers. The duration of the study was from February 1, 2018 to May 31, 2020. We divided the population into two groups. The first group, consists of patients with primary lung cancer who are also smokers that have been exposed to occupational exposure for at least 10 years, while the second group, lacks the occupational exposure factor.
RESULTS.The average age of onset of lung cancer in patients was statistically, significantly lower in occupationally exposed patients, than in non-occupationally exposed patients. More specifically, the average age of onset of lung cancer in occupationally exposed patients, was 65.5 years and the average age of onset of lung cancer in non-occupationally exposed patients, was 72.6 years. In addition, the average age of onset of respiratory failure, was statistically, significantly lower in occupationally exposed patients, than in non-occupationally exposed patients. More specifically, the average age of onset of respiratory failure in occupationally exposed patients, was 65.9 years and the average age of onset of respiratory failure in non-occupationally exposed patients, was 73.7 years.
CONCLUSION: It seems that exposure of smokers to inhaled substances in their working environment, leads to earlier lung cancer and respiratory failure, compared to the non-exposed workers.
Keywords:
Lung cancer, Occupational exposure, Smoking, Respiratory failure, Greece