The role of cortisone and cortisol in chronic pain

Postgraduate Thesis uoadl:2967283 1 Read counter

Κατεύθυνση Αλγολογία: Αντιμετώπιση του πόνου, διάγνωση και θεραπεία. Φαρμακευτικές, παρεμβατικές και άλλες τεχνικές
Library of the School of Health Sciences
Deposit date:
Konstantinidis Athanasios
Supervisors info:
Αικατερίνη Μελεμενή, Αναπληρώτρια καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Άντεια Παρασκευά, Αναπληρώτρια καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Αθανασία Τσαρουχά, Αναπληρώτρια καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Η επίδραση της κορτιζόνης και της κορτιζόλης στον χρόνιο πόνο
Translated title:
The role of cortisone and cortisol in chronic pain
The aim of this dissertation is to study the effect of cortisol and cortisone on chronic
pain. The methodology deemed appropriate for conducting the research is the literature
review. The bibliography used includes books, articles from scientific journals and
research either in print or online and the theoretical background of the research is based
on it. Through the critical evaluation of the literature, the conclusions of the research
emerged. The search for scientific material began on March 15, 2021 and ended on May
10, 2021. The search was done in the databases: Google Scholar, Elsevier and Pubmend
and the keywords used are: "HPA axis", "chronic pain" , "cortisol","cortisone",
"chronic stress" . The findings of the study are that cortisol and cortisone have a
regulatory role in the functioning of the HPA axis when the body is under conditions
of intense physical or emotional stress. This helps to avoid the maladaptive situations
that can be caused by the uncontrolled operation of the HPA axis in chronic pain which
can make its intensity and duration more intense.
Main subject category:
Health Sciences
Axis HPA, Chronic pain, Cortisol, Cortisone, Chronic stress
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