Dissertation committee:
Αλέξανδρος Στρατηγός, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Χριστίνα Αντωνίου, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Χρήστος Χριστοδούλου, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Αργυρώ Χατζηιωάννου, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Δημήτριος Δικαίος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Δημήτριος Ρηγόπουλος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Γρηγορίου Σταμάτιος, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Summary:
This paper will focus mainly on the action of botulinum toxin type A in Cosmetic Dermatology and what may be its effect on the quality of life of patients. The history of botulinum toxin dates back to the early 19th century when the first description of botulism was made by a naturalist of the time, Justinus Kerner, in Germany. Its mechanism of action is described as a chemical denervation, which blocks the peripheral release of acetylcholine at presynaptic cholinergic terminals through the degradation of SNAP-25, a protein essential for the successful attachment and release of acetylsorphins nerve endings.
This dissertation deals with the use of botulinum toxin and its effect after use on human quality of life. It consists of two parts, the theoretical part, which analyzes health, deepens the quality of life in general and in the light of other sciences, analyzes the measurement of quality of life, aesthetics and beauty, botulinum toxin and non-surgical interventions. The second part deals with the research part, which presents the questionnaires distributed to patients, the unit of measurement used to evaluate the questions, the results given by the respondents and the conclusions drawn through the questionnaires.
