Neurophysiological and neuroplastic impact of exercise with and without blood flow restriction after spinal cord injury

Postgraduate Thesis uoadl:3328773 41 Read counter

Unit:
Κατεύθυνση Αποκατάσταση Βλαβών Νωτιαίου Μυελού. Διαχείριση του πόνου Σπονδυλικής προέλευσης
Library of the School of Health Sciences
Deposit date:
2023-05-22
Year:
2023
Author:
Giannopoulou Maria
Supervisors info:
Ιωάννης Βλάμης, Αναπληρωτής Καθηγητής, Ιατρική Σχολή , ΕΚΠΑ
Δημήτριος-Στέργιος Ευαγγελόπουλος, Μεταδιδακτορικός Ερευνητής, Ιατρική Σχολή, ΕΚΠΑ
Ιωάννης Μπενέτος, Μεταδιδακτορικός Ερευνητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Η νευροφυσιολογική και νευροπλαστική επίδραση της άσκησης με και χωρίς περιορισμό αιματικής ροής σε ασθενείς μετά από κάκωση νωτιαίου μυελού
Languages:
Greek
Translated title:
Neurophysiological and neuroplastic impact of exercise with and without blood flow restriction after spinal cord injury
Summary:
Spinal cord injury (SCI) leads to a multiple of long-term functional deficits, which
significantly affect the quality of life of the patients. Exercise appears to have a
broad neurobiological effect on the peripheral and central nervous systems (CNS).
However, although the exact mechanisms by which this occurs are still under
investigation, significant progress has been made in recent years to understand
the cellular and molecular basis of exercise in patients with SCI. The present
literature review highlights the neurophysiological, neuroprotective and
neuroregenerative value of exercise theraoy in patients with SCI. The presumable
physiological mechanisms of exercise with blood flow restriction (BFR) technique
in this population are also presented. For the purpose of the study, the literature
was searched in the databases MEDLINE / PubMed, Scopus, PEDro and
Cochrane Library. The keywords used were: "spinal cord injury", "exercise",
"physical therapy", "rehabilitation", "blood flow restriction", "regeneration",
"neuroplasticity". The search strategy was tailored to each database requirements.
The literature review shows that exercise can have significant regulatory benefits
in the CNS of patients with SCI. Although the mechanisms of action are not yet
sufficiently documented, at the preclinical and clinical level the exercise does
indeed appear to have a neuroprotective and neuroregenerative potential acting
both locally and systemically. The implementation of exercise therapy programs in
patients with SCI is considered necessary, not only based on the early findings at
the neurophysiological level, but also due to the overall benefits it could have on
other biological systems. In future studies, it is suggested a further research of the
effects of exercise with BFR in patients with SCI and the investigation for the
appropriate timing of implementation of the exercise programs, as well as their
quantification regarding volume, duration, frequency and intensity of the programs.
Main subject category:
Health Sciences
Keywords:
Spinal cord injury, Exercise therapy, Rehabilitation, Neurophysiology, Blood flow restriction
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
196
Number of pages:
48
File:
File access is restricted only to the intranet of UoA.

Giannopoulou_Maria_MSc.pdf.pdf
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