Clinical course of covid infection in patients presenting with neurological symptoms

Postgraduate Thesis uoadl:3405705 18 Read counter

Unit:
Κατεύθυνση Καρκίνος Πνεύμονα: Σύγχρονη Κλινικοεργαστηριακή Προσέγγιση και Έρευνα
Library of the School of Health Sciences
Deposit date:
2024-07-25
Year:
2024
Author:
Αmanatidou Anastasia
Supervisors info:
Ανδριανή Χαρπίδου ,Επιστημονική Συνεργάτης, Ιατρική Σχολή, ΕΚΠΑ
Ηλίας Κοττέας,Αναπληρωτής Καθηγητής Ιατρική Σχολή, ΕΚΠΑ
Γαρυφαλλιά Πουλάκου, Αναπληρώτρια Καθηγήτρια ,Ιατρική Σχολή ΕΚΠΑ
Original Title:
Κλινική πορεία covid λοίμωξης σε ασθενείς που εμφάνισαν νευρολογικά συμπτώματα
Languages:
Greek
Translated title:
Clinical course of covid infection in patients presenting with neurological symptoms
Summary:
The purpose of the present study is to provide data regarding the neurological findings during the acute phase of covid-19 infection, to study the post-covid-19 neurological effects of patients as well as to achieve a correlation of demographic and clinical data with the above.
So, initially the literature is extensively studied and the appropriate 2-part questionnaire is created: Demographic data and post-covid neurological effects which is distributed to 25 patients, who hospitalized at the Xanthi’s General Hospital and were checked through a brain Computed Tomography (CT) scan. Participants are 72% male, 84% over 50 years of age with half having had at least one dose of vaccine, 75% having a major comorbidity and 24% dying.
Regarding the post-covid effects, it is identified that they are present in almost half of the patients who survived hospitalization, and then they are carefully presented with the results showing that attention deficit and anxiety disorder are the main ones in 20% and it is shown that they appear within 2 months in 96% of the patients.
Then, after being categorized based on their severity into primary secondary and other, the brain CT findings are presented. It is important to emphasize that almost 50% of the patients experienced an ischemic stroke while only one patient showed neither primary nor secondary symptoms.
Finally, an attempt is made to correlate the main variables of the study through a Fisher-Freeman-Halton analysis. A statistically significant correlation is shown for the variables of comorbidity-mortality rate (those with none/low comorbidity where all survived the disease), comorbidity-occurrence of ischemic stroke in the brain CT (those who showed high/very high comorbidity in a percentage greater than 90%) and appearance of primary brain CT symptoms-mortality (all deaths -6 people- come from people with at least one primary brain CT finding). The above findings are all in agreement with the literature. The main conclusion of the current study, therefore, is that the study of brain CTs of patients and their co-morbidity gives strong clues about the progression of the disease.
Main subject category:
Health Sciences
Keywords:
COVID infection, Neurological symptoms
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
76
Number of pages:
60
File:
File access is restricted only to the intranet of UoA.

Διπλωματική Εργασία Αμανατίδου final (1).pdf
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