Τίτλος:
Nuchal-type fibroma: Single-center experience and systematic literature review
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Nuchal-type fibroma is a rare benign tumor arising from the connective tissue. Our aim was to present our experience via two cases of this tumor and a comprehensive review of the literature. Patients and Methods: We report a case of a 23-year-old female with a mass located in the posterior neck and the upper back and a case of a 50-year-old male with a mass located in the posterior neck, which were proved to be nuchal-type fibromas in the histopathological examination. We also searched the PubMed/Medline database for published cases of nuchal-type fibromas. Results and Discussion: Nuchaltype fibroma is a rare benign tumor arising from the connective tissue, usually in the posterior neck, which affects different ages, with most patients being male. It is a poorly circumscribed tumor consisting of hypocellular, thick, dense and haphazardly arranged collagen bundles with entrapped adipocytes, nerve fibers and muscle fascicles and a few scattered spindle cells, which are CD34 positive. Its excision is curative, and the recurrence risk is generally low. However, patients with Gardner's syndrome may experience recurrence more frequently. Conclusion: Nuchal-type fibroma should be included in the differential diagnosis of subcutaneous, soft-tissue masses, especially when these involve the posterior neck. © 2020 International Institute of Anticancer Research. All rights reserved.
Συγγραφείς:
Kostakis, I.D.
Feretis, T.
Damaskos, C.
Garmpis, N.
Liapis, G.
Pateras, I.
Garmpi, A.
Georgakopoulou, V.E.
Antoniou, E.A.
Περιοδικό:
In vivo (Athens, Greece)
Εκδότης:
International Institute of Anticancer Research
Λέξεις-κλειδιά:
adult; Article; case report; clinical article; contrast enhancement; data base; excision; female; fibroma; histopathology; human; human cell; immunohistochemistry; male; middle aged; muscle; nape; nuclear magnetic resonance imaging; splenius muscle; systematic review; trapezius muscle; tumor volume; young adult; differential diagnosis; Gardner syndrome; genetics; head and neck tumor; neck; tumor recurrence, Adult; Diagnosis, Differential; Female; Fibroma; Gardner Syndrome; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neck; Neoplasm Recurrence, Local; Young Adult
DOI:
10.21873/invivo.12032
