Περίληψη:
The score based on the office systolic blood pressure, age, fasting blood glucose level, and estimated glomerular filtration rate (SAGE score) has been proposed as a useful marker to identify elevated values of carotid-femoral pulse wave velocity (PWV). The present cross-sectional study was conducted to examine whether the SAGE score is also a useful marker to identify subjects with elevated brachial-ankle PWV values in Japanese subjects with hypertension. We measured the brachial-ankle PWV and calculated the SAGE score in a total of 1019 employees of a Japanese company with hypertension and 817 subjects with hypertension derived from a multicenter study cohort. The analyses in this study were based on data from these two study groups as well as on a composite population of the two (n = 1836). The receiver operating characteristic curve analysis showed that the area under the curve to identify subjects with brachial-ankle PWV values of ≥1800 cm/s was over 0.70 in each of the three study groups. Even after adjustments, a SAGE score ≥7 had a significant odds ratio for identifying subjects with brachial-ankle PWV values ≥1800 cm/s in the 1836 study subjects from the composite occupational and multicenter study cohort (odds ratio = 2.1, 95% confidence interval = 1.4–3.0, P < 0.01). Thus, in Japanese subjects with hypertension, the SAGE score may be a useful marker for identifying subjects with elevated brachial-ankle PWV values. © 2020, The Japanese Society of Hypertension.
Συγγραφείς:
Tomiyama, H.
Vlachopoulos, C.
Xaplanteris, P.
Nakano, H.
Shiina, K.
Ishizu, T.
Kohro, T.
Higashi, Y.
Takase, B.
Suzuki, T.
Yamazaki, T.
Furumoto, T.
Kario, K.
Inoue, T.
Koba, S.
Takemoto, Y.
Hano, T.
Sata, M.
Ishibashi, Y.
Node, K.
Tanaka, A.
Maemura, K.
Ohya, Y.
Furukawa, T.
Ito, H.
Ohkuma, T.
Ninomiya, T.
Chikamori, T.
Yamashina, A.
Ueda, S.-I.
Λέξεις-κλειδιά:
cholesterol; creatinine; high density lipoprotein cholesterol, adult; aged; Article; atrial fibrillation; brachial-ankle pulse wave velocity; Chronic Kidney Disease Epidemiology Collaboration equation; cohort analysis; controlled study; cross-sectional study; diagnostic test accuracy study; diastolic blood pressure; estimated glomerular filtration rate; female; glucose blood level; human; hypertension; Japanese (people); kidney function; major clinical study; male; mathematical parameters; multicenter study; observational study; prospective study; receiver operating characteristic; SAGE score; scoring system; sensitivity and specificity; systolic blood pressure; waveform; health status indicator; hypertension; Japan; middle aged; pathophysiology; pulse wave, Adult; Aged; Cross-Sectional Studies; Female; Health Status Indicators; Humans; Hypertension; Japan; Male; Middle Aged; Pulse Wave Analysis
