National curves of foetal growth in singleton foetuses of Greek origin

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3086424 17 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
National curves of foetal growth in singleton foetuses of Greek origin
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Foetal growth monitoring is an essential component of prenatal care with postnatal impact. The aim of the study was to construct reference ranges for foetal biometric parameters in Greek foetuses and to compare them with previously published models. Materials and Methods: Measurements from 1200 Greek foetuses were used to construct normal curves for biparietal diameter (BPD), occipitofrontal diameter (OFD), head circumference (HC), abdominal circumference (AC), femoral length (FL) and the BPD/FL ratio according to the methodology described by Royston and Wright (1998). The model was validated in a second group of 1200 different foetuses using analysis of the corresponding standardized residuals (z-scores). The z-scores which were derived by our model were compared to those calculated using previously published models from other populations. Results: BPD, OFD, HC, AC, FL and the BPD/FL ratio are accurately described by simple quadratic equations (R2 > 0·96 for most of the parameters tested). Statistically significant differences were observed for most of the z-scores when our models were compared to previously published models. Less than 10% of our foetuses were < 5th or > 95th centile of the latter models. About 10% of our foetuses were > 95th centile for FL and HC when the INTERGROWTH-21st formulas were used. Conclusion: We present national foetal biometric references. Using charts from other populations (including INTERGROWTH-21st) may be unrepresentative of local populations and lead to misclassification of foetal growth status. © 2016 Stichting European Society for Clinical Investigation Journal Foundation. Published by John Wiley & Sons Ltd.
Έτος δημοσίευσης:
2016
Συγγραφείς:
Sotiriadis, A.
Eleftheriades, M.
Chatzinikolaou, F.
Hassiakos, D.
Chrousos, G.P.
Pervanidou, P.
Περιοδικό:
European Journal of Clinical Investigation
Εκδότης:
Wiley-Blackwell Publishing Ltd
Τόμος:
46
Αριθμός / τεύχος:
5
Σελίδες:
425-433
Λέξεις-κλειδιά:
abdominal circumference; adult; anthropometric parameters; Article; biometry; biparietal distance; brain size; comparative study; controlled study; female; femoral length; femur diaphysis; fetus; fetus echography; fetus growth; gestational age; Greece; growth curve; head circumference; human; maternal age; observational study; occipitofrontal diameter; priority journal; prospective study; third trimester pregnancy; abdomen; anthropometry; Caucasian; cephalometry; diagnostic imaging; episodic memory; femur; fetus development; gestational age; growth curve; head; pregnancy; reference value; second trimester pregnancy, Abdomen; Adult; Anthropometry; Biometry; Cephalometry; European Continental Ancestry Group; Female; Femur; Fetal Development; Fetus; Gestational Age; Greece; Growth Charts; Head; Humans; Memory, Episodic; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Reference Values; Ultrasonography, Prenatal
Επίσημο URL (Εκδότης):
DOI:
10.1111/eci.12611
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