Unusual abscess masquerading as poorly differentiated adenocarcinoma of the colon showing characteristics of choriocarcinoma

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3104898 15 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Unusual abscess masquerading as poorly differentiated adenocarcinoma of the colon showing characteristics of choriocarcinoma
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Extragonadal non-gestational choriocarcinoma (ENC) is an uncommon malignant tumor occasionally found in the gastrointestinal tract. ENC is characterized by a biphasic tumor growth with distinct areas of adenocarcinoma and choriocarcinoma differentiation. Primary choriocarcinoma of the colon is extremely rare, with only 21 cases reported in the literature. Most of the perforation of colorectal cancers occurs in the abdominal cavity, while abdominal wall abscess is rare; the psoas abscess associated with colon carcinoma is even less observed. Herein, we report the case of a 61-year-old female with poorly differentiated adenocarcinoma of the ascending colon and sigmoid, with choriocarcinomatous differentiation, masquerading a psoas abscess formation. Unfortunately, despite the aggressive therapy, the patient’s disease rapidly progressed, and she died within 2 months after the diagnosis. The typical morphological pattern, immunohistochemistry, and its correlation with serum β-human chorionic gonadotropin enabled a correct diagnosis. © 2020, Hospital Universitario da Universidade de Sao Paulo. All rights reserved.
Έτος δημοσίευσης:
2020
Συγγραφείς:
Mitselou, A.
Varouktsi, A.
Papadatos, S.S.
Balasi, E.
Lampri, E.
Katsanos, K.
Galani, V.
Περιοδικό:
Autopsy and Case Reports
Εκδότης:
Hospital Universitario da Universidade de Sao Paulo
Τόμος:
10
Αριθμός / τεύχος:
3
Επίσημο URL (Εκδότης):
DOI:
10.4322/acr.2020.145
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.