Περίληψη:
Malnutrition is a common finding in cancer patients, which can affect disease progression and survival. This review aims to critically summarize the prognostic role of nutritional status, from Body Mass Index (BMI) and weight loss to nutrition screening tools and biochemical indices, in cancer patients. According to the currently available data, Prognostic Nutritional Index (PNI) was a significant prognostic factor of patients' survival, both in univariate and multivariate analyses. Pre-operative albumin was also correlated with worse outcomes, being an independent prognostic factor of survival in several studies. BMI was also well-studied, with contradictory results. Although, lower BMI was found to be an independent prognostic factor of shorter survival in some studies, in others it did not have an impact on survival. In this aspect, this review highlights the significant prognostic role of nutritional status in the disease progression and survival of cancer patients. Further, good-quality prospective studies are needed in order to draw precise conclusions on the prognostic role of specific nutritional assessment tools, and biochemical indices associated with the nutritional status in more cancer types, such as liver, breast and prostate cancer, and hematological malignancies. © 2017 Taylor & Francis Group, LLC.
Συγγραφείς:
Mantzorou, M.
Koutelidakis, A.
Theocharis, S.
Giaginis, C.
Λέξεις-κλειδιά:
albumin, body mass; breast cancer; cancer chemotherapy; cancer growth; cancer palliative therapy; cancer patient; cancer prognosis; cancer recurrence; cancer surgery; cancer survival; cancer survivor; childhood cancer; colorectal cancer; disease free survival; follow up; glioblastoma; head and neck cancer; hematologic malignancy; Hospital Anxiety and Depression Scale; hospitalization; human; Karnofsky Performance Status; kidney cancer; liver cancer; lung cancer; lymphoma; malignant neoplasm; malnutrition; median survival time; medical record; mortality risk; neuroblastoma; neutrophil lymphocyte ratio; nutritional assessment; nutritional status; nutritional support; outcome assessment; ovary cancer; pancreas cancer; platelet lymphocyte ratio; prostate cancer; Review; screening test; stomach cancer; treatment failure; weight change; weight reduction; body weight loss; disease exacerbation; female; male; malnutrition; neoplasm; nutritional assessment; prognosis; randomized controlled trial (topic); risk factor, Body Mass Index; Disease Progression; Female; Humans; Male; Malnutrition; Neoplasms; Nutrition Assessment; Nutritional Status; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Weight Loss
