Τίτλος:
The Role of Disorganization of Retinal Inner Layers as Predictive Factor of Postoperative Outcome in Patients with Epiretinal Membrane
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: The purpose of this retrospective study was to evaluate the disorganization of the retinal inner layers (DRIL) as a potential predictive factor of postoperative visual outcome in patients with idiopathic epiretinal membrane (iERM), treated with pars plana vitrectomy (PPV). Methods: Participants in the study were 46 consecutive patients diagnosed with iERM, who underwent PPV. Best corrected visual acuity (BCVA) measurement and spectral-domain optical coherence tomography (SD-OCT) were performed at baseline (preoperatively), and at months 3 and 6 postoperatively. DRIL and additional OCT parameters were assessed at 1-mm-wide foveal centered area. Results: DRIL was observed in 47.8% of patients at baseline. There was statistically significant improvement in BCVA and central retinal thickness (CRT) between baseline and months 6 and 12 in all patients. There was a statistically significant difference in BCVA and CRT change between patients with and without DRIL at months 6 and 12 compared to baseline, showing that there was a correlation between change in BCVA or CRT and baseline DRIL. Ellipsoid zone and external limiting membrane were intact in 91.3 and 95.7%, respectively, not affecting our results. Conclusions: Baseline DRIL has been shown to be predictive of postoperative visual outcome in patients with iERM, treated with PPV. © 2019 © 2019 S. Karger AG, Basel.
Συγγραφείς:
Garnavou-Xirou, C.
Xirou, T.
Gkizis, I.
Kabanarou, S.A.
Dimitriou, E.
Theodossiadis, P.
Chatziralli, I.
Περιοδικό:
Ophthalmic Research
Λέξεις-κλειδιά:
aged; Article; best corrected visual acuity; central retinal thickness; clinical article; correlation analysis; epiretinal membrane; external limiting membrane; female; human; male; pars plana vitrectomy; postoperative period; prediction; preoperative evaluation; priority journal; prognosis; retina fovea; retinal inner nuclear layer; retinal inner plexiform layer; retrospective study; spectral domain optical coherence tomography; treatment outcome; fluorescence angiography; middle aged; optical coherence tomography; pathology; predictive value; retina; very elderly; vitrectomy, Aged; Aged, 80 and over; Epiretinal Membrane; Female; Fluorescein Angiography; Humans; Male; Middle Aged; Predictive Value of Tests; Retina; Retrospective Studies; Tomography, Optical Coherence; Vitrectomy
