Τίτλος:
Chemical composition and antimicrobial activity of geniosporum rotundifolium briq and haumaniastrum villosum (Bene) AJ Paton (Lamiaceae) essential oils from Tanzania
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: To determine the chemical composition and antimicrobial potential of essential oils from two aromatic plants of Tanzania, Geniosporum rotundifolium Briq. and Haumaniastrum villosum (Benè) A.J. Paton (Lamiaceae). Method: Essential oils from the aerial parts of the plants were extracted by hydro-distillation for 3 h using a Clevenger type of apparatus. The constituents were analyzed by gas chromatography – mass spectrometry (GC/MS).The minimum inhibitory concentrations of the essential oils were determined for eight bacterial strains and three pathogenic fungi using agar dilution method. Results: The constituents of G. rotundifolium oil were mainly oxygenated derivatives of mono- and sesquiterpenes; spathulenol (12.46 %), α-terpineol (4.65 %) and germacrene-D (3.71 %) were the most abundant. Those of H. villosum oil were predominantly sesquiterpenes (72.61 %) with caryophyllene oxide (19.01 %), humulene epoxide II (11.95 %), β-bourbonene (5.7 %), α-humulene (5.63 %) and β- caryophyllene (5.39 %) being more abundant. The oil of G. rotundifolium exhibited weak to moderate activity against the bacterial species but showed no activity against the test fungi. However, H. villosum oil showed very promising activity against all the test microorganisms (MIC 0.08 – 10.34 mg/mL). Conclusion: The major components of G. rotundifolium essential oil were oxygenated derivatives of mono- and sesquiterpenes whereas those of H. villosum were sesquiterpenes. All tested microorganisms were susceptible to H. villosum oil. © Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. All rights reserved.
Συγγραφείς:
Ngassapa, O.D.
Runyoro, D.K.B.
Vagionas, K.
Graikou, K.
Chinou, I.B.
Περιοδικό:
Tropical Journal of Pharmaceutical Research
Εκδότης:
Faculty of Pharmacy, University of Benin
Λέξεις-κλειδιά:
1 octen 3 ol; 3 octanol; absinthol; amoxicillin; beta pinene; bourbonene; camphene; camphor; caryophyllene; caryophyllene oxide; cineole; essential oil; Geniosporum rotundifolium extract; germacrene D; Haumaniastrum villosum extract; humulene; humulene epoxide 2; limonene; linalool; netilmicin; ocimene; para cymene; pinene; plant extract; sesquiterpene; spathulenol; terpinene; terpineol; terpinolene; unclassified drug; unindexed drug, antimicrobial activity; Article; chemical composition; controlled study; extraction; mass fragmentography; minimum inhibitory concentration; nonhuman; Tanzania
DOI:
10.4314/tjpr.v15i1.15
