Τίτλος:
Vagiallene, a Rearranged C 15 Acetogenin from Laurencia obtusa
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Vagiallene (1), a rearranged C 15 acetogenin with a molecular formula and a carbon skeleton unprecedented in natural products, was isolated as a trace constituent from the organic extract of the red alga Laurencia obtusa from Lefkada island. The planar structure and the relative configuration of 1 were established on the basis of extensive analysis of its spectroscopic data, while its absolute configuration was determined by comparison of its experimental and quantum-mechanically predicted electronic circular dichroism spectra. © 2019 American Chemical Society.
Συγγραφείς:
Perdikaris, S.
Mangoni, A.
Grauso, L.
Papazafiri, P.
Roussis, V.
Ioannou, E.
Περιοδικό:
Organic Letters
Εκδότης:
American Chemical Society
Λέξεις-κλειδιά:
acetogenin; antineoplastic agent; plant extract, cell survival; chemical structure; chemistry; conformation; drug effect; human; isolation and purification; isomerism; Laurencia; molecular dynamics; quantum theory; thermodynamics; tumor cell line, Acetogenins; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Humans; Isomerism; Laurencia; Molecular Conformation; Molecular Dynamics Simulation; Molecular Structure; Plant Extracts; Quantum Theory; Thermodynamics
DOI:
10.1021/acs.orglett.9b00897
