Τίτλος:
Percutaneous Navigation under Local Anesthesia for Computed
Tomography-Guided Microwave Ablation of Malignant Liver Lesions Located
in the Hepatic Dome
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background and Objectives: The aim of the present study was to report
the safety and efficacy of percutaneous navigation under local
anesthesia for computed tomography-guided microwave ablation of
malignant liver lesions located in the hepatic dome. Patients with
primary and secondary malignant liver lesions located in the hepatic
dome who underwent percutaneous computed tomography-guided microwave
ablation using a computer-assisted navigation system under local
anesthesia were prospectively evaluated. The primary objective was
technical success. Materials and Methods: The sample consisted of 10
participants (16 lesions) with a mean age of 60.60 years (SD = 9.25
years) and a mean size of 20.37 inverted iota 7.29 cm, and the mean
follow-up time was 3.4 months (SD = 1.41) months. Results: Primary
technical success was 93.75%. Tumor remnant was noticed at one month
follow-up in a single metastatic lesion, which was re-treated with an
ablation session, and no tumor remnant was depicted in the subsequent
imaging follow-up (secondary technical success 100%). Grade I
self-limited complications (according to the CIRSE classification
system) included small pleural effusion (n = 1) and minor bleeding post
antenna removal (n = 1) requiring nothing but observation. Conclusions:
the findings of the present study indicate that percutaneous navigation
under local anesthesia is a safe and efficacious approach for computed
tomography-guided microwave ablation of malignant liver lesions located
in the hepatic dome. Large randomized controlled studies are warranted
to observe treatment effectiveness and compare the results with those of
other options.
Συγγραφείς:
Filippiadis, Dimitrios K.
Velonakis, Georgios
Mazioti, Argyro
and Tsochatzis, Athanasios
Vrachliotis, Thomas
Kelekis, Alexis
and Kelekis, Nikolaos
Περιοδικό:
MEDICINA-LITHUANIA
Λέξεις-κλειδιά:
microwave ablation; navigation; computed tomography; local anesthesia;
hepatocellular carcinoma; metastasis
DOI:
10.3390/medicina57101056
