Τίτλος:
Diagnosis and treatment complications of primary cardiac lymphoma in an immunocompetent 28-year old man: A case report
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Primary cardiac lymphomas (PCL) represent extremely rare cardiac tumors which are accompanied by poor prognosis, unless they are timely diagnosed and treated. Case presentation: Herein we present a 28-year-old, immunocompetent man who presented to our hospital due to progressively worsening symptoms and signs of superior vena cava syndrome. Multi-modality imaging demonstrated a large intracardiac tumor, which was proven, by biopsy, to be a PCL. The patient received targeted chemotherapy which led to total remission of his disease, with no relapse over a 15-month follow-up period. Conclusions: Although PCLs are rare, they should always be kept in mind in the differential diagnosis of cardiac tumors. Timely diagnosis of PCLs and appropriate chemotherapy, alone or in combination with radiotherapy, seems to provide the best results. © 2019 The Author(s).
Συγγραφείς:
Bonou, M.
Kapelios, C.J.
Marinakos, A.
Adamopoulos, S.
Diamantopoulos, P.
Foukas, P.G.
Kaklamanis, L.
Korkolopoulou, P.
Barbetseas, J.
Viniou, N.-A.
Εκδότης:
BioMed Central Ltd.
Λέξεις-κλειδιά:
C reactive protein; cyclophosphamide; D dimer; doxorubicin; prednisolone; prednisone; rituximab; thyrotropin; troponin T; vincristine; antineoplastic agent; cyclophosphamide; doxorubicin; monoclonal antibody; prednisone; R-CHOP protocol; vincristine, adult; Article; bradycardia; case report; clinical article; clinical feature; diffuse large B cell lymphoma; disease exacerbation; disease severity; drug efficacy; drug safety; erythema; face edema; follow up; heart muscle biopsy; heart tumor; histopathology; human; human tissue; immunophenotyping; male; physical examination; primary cardiac lymphoma; remission; superior cava vein; superior cava vein syndrome; thorax radiography; transesophageal echocardiography; transthoracic echocardiography; cine magnetic resonance imaging; complication; echocardiography; heart arrhythmia; heart tumor; pathology; positron emission tomography-computed tomography; superior cava vein syndrome, Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Cyclophosphamide; Doxorubicin; Echocardiography; Heart Neoplasms; Humans; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging, Cine; Male; Physical Examination; Positron Emission Tomography Computed Tomography; Prednisone; Remission Induction; Superior Vena Cava Syndrome; Vincristine
DOI:
10.1186/s12885-019-5405-y
