Τίτλος:
Evaluation of liver fibrosis: “Something old, something new…”
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Hepatic fibrogenesis may gradually result to cirrhosis due to the accumulation of extracellular matrix components as a response to liver injury. Thus, therapeutic decisions in chronic liver disease, regardless of the cause, should first and foremost be guided by an accurate quantification of hepatic fibrosis. Detection and assessment of the extent of hepatic fibrosis represent a challenge in modern Hepatology. Although traditional histological staging systems remain the “best standard”, they are not able to quantify liver fibrosis as a dynamic process and may not accurately substage cirrhosis. This review aims to compare the currently used non-invasive methods of measuring liver fibrosis and provide an update in current tissue-based digital techniques developed for this purpose, that may prove of value in daily clinical practice. © 2016 Hellenic Society of Gastroenterology.
Συγγραφείς:
Almpanis, Z.
Demonakou, M.
Tiniakos, D.G.
Περιοδικό:
ANNALS OF GASTROENTEROLOGY
Εκδότης:
Hellenic Society of Gastroenterology
Λέξεις-κλειδιά:
biological marker; gelatinase A; hyaluronic acid; interstitial collagenase; laminin; procollagen; procollagen type 3; tissue inhibitor of metalloproteinase; transforming growth factor beta1; unclassified drug, acoustic radiation force impulse imaging; BAAT score; BARD score; contrast enhancement; diagnostic accuracy; digestive diagnostic device; digestive system disease assessment; disease severity; elastograph; elastography; European Liver Fibrosis panel; FIB 4 score; Fibrometer; Fibrospect; Forn score; Hepascore; histology; human; liver biopsy; liver cirrhosis; liver fibrosis; liver function test kit; magnetic resonance elastography; NAFLD fibrosis score; nonalcoholic fatty liver; predictive value; prognosis; real time echography; Review; sensitivity and specificity; serology; transient elastography; two dimensional shear wave elastography; validation process; venous pressure
DOI:
10.20524/aog.2016.0046
