Τίτλος:
Desmoplastic small round cell tumor of the pleura
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Desmoplastic small round cell tumor (DSRCT) is a rare neoplasm with
aggressive behavior. Usually it presents as a peritoneal mass, although
other cases in various locations have been described. Since less than 10
cases of primary DSRCT in the pleura have been described, it is of
interest to report a pediatric case arising from the pleura. The
diagnosis was confirmed by molecular detection of the EWS/WT-1 fusion
gene product. Multidisciplinary treatment with chemotherapy,
radiotherapy, and surgical resection resulted in a progression-free
survival time above the median survival, suggesting that this
conventional approach could prove effective for this rare and very
aggressive malignancy.
Συγγραφείς:
Karavitakis, Emmanouil M.
Moschovi, Maria
Stefanaki, Kalliopi
and Karamolegou, KaIlliopi
Dimitriadis, Euthimios
Pandis, Nikos
and Karakousis, Constantine P.
Tzortzatou-Stathopoulou, Fotini
Περιοδικό:
Pediatric Blood and Cancer
Εκδότης:
Wiley-Liss, Inc.
Λέξεις-κλειδιά:
childhood; desmoplastic small round cell tumor; multidisciplinary
treatment; pleura
