Ερευνητικό υλικό ΕΚΠΑ

The management of HCV infected pregnant women and their children European paediatric HCV network

Αγγλικά

Background/Aims: As evidence accumulates relating to mother-to-child (vertical) transmission of hepatitis C virus (HCV), it is timely to draw up guidelines for the clinical management of HCV infected pregnant women and their children. Methods: A review of evidence from the European Paediatric HCV Network (EPHN) prospective study of HCV infected women and their children and other published studies. Meeting of EPHN clinical experts to reach a consensus on recommendations for management. Each recommendation was graded according to the level of evidence. Results/conclusions: Although several risk factors for mother-to-child transmission have been identified, none are modifiable and there are currently no interventions available to prevent vertical transmission of HCV. Data on timing of loss of maternal antibodies and reliability of diagnostic tests inform the optimum follow-up schedule for confirmation or exclusion of infection in children born to HCV infected women. Based on the current evidence, routine antenatal screening for HCV should not be introduced and neither elective caesarean section nor avoidance of breastfeeding should be recommended to HCV infected women to prevent mother-to-child transmission of HCV. HCV/HIV co-infected women should follow existing HIV guidelines. © 2005 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

2005

Pembrey, L.
Newell, M.-L.
Tovo, P.-A.
Amoroso, A.
Bevilaqua, E.
Asensi-Botet, F.
Pereda, A.
Balossini, V.
Bona, G.
Zaffaroni, M.
Bandelloni, A.
Coscia, A.
Fabris, C.
Aime, S.
Belloni, C.
Bossi, G.
Salati, B.
Boucher, C.
Buffolano, W.
Butler, K.
Roura, L.C.
Sanges, J.M.B.
Cigna, P.
Ciria, L.M.
Ginard, C.S.
Teruel, G.C.
Fortuny, C.
Coll, O.
Corrias, A.
Ledda, R.
Floris, S.
De Maria, A.
Echeverria, J.
Cilla, G.
Faldella, G.
Lanari, M.
Tridapalli, E.
Venturi, V.
Fischler, B.
Bohlin, A.-B.
Lindgren, S.
Lindh, G.
Giacomet, V.
Merlo, M.
Figini, C.
Erba, P.
Viganò, A.
Hannam, S.
Mieli-Vergani, G.
Hatzakis, A.
Inchley, C.
Fjaerli, H.O.
Maccabruni, A.
Marcellini, M.
Sartorelli, M.R.
Fontelos, P.M.
Mazza, A.
Mok, J.Y.Q.
Mûr, A.
Viñolas, M.
Paternoster, D.M.
Grella, P.
Polywka, S.
Quinti, I.
Casadei, A.M.
Rojahn, A.
Berg, A.
Rosso, R.
Ferrando, S.
Bassetti, D.
Contreras, J.R.
Manzanares, A.
Extremera, A.R.
Salvini, F.
Zuccotti, G.V.
Schmitz, T.
Grosch-Wörner, I.
Sperling, C.F.
Piening, T.
Vegnente, A.
Iorio, R.
Versace, A.
Lazier, L.
Palomba, E.
Gabiano, C.
Balbo, L.
Zanetti, A.
Tanzi, E.

WORLD JOURNAL OF HEPATOLOGY

Elsevier B.V.

43

3

515-525

maternal antibody; peginterferon; recombinant alpha interferon; recombinant alpha2b interferon; ribavirin, anorexia; body weight disorder; breast feeding; cesarean section; child; childhood disease; clinical protocol; diagnostic accuracy; diagnostic test; evidence based medicine; fatigue; female; flu like syndrome; follow up; gestation period; hepatitis C; Hepatitis C virus; human; Human immunodeficiency virus infection; infection risk; intrauterine infection; practice guideline; pregnancy; prenatal screening; priority journal; prospective study; reliability; review; superinfection; vertical transmission; virus infectivity; virus transmission; weight reduction

https://doi.org/10.1016/j.jhep.2005.06.002

10.1016/j.jhep.2005.06.002

https://pergamos.lib.uoa.gr/uoa/dl/object/3134779