Κατεύθυνση ΒιοστατιστικήLibrary of the School of Health Sciences
Κλέα Κατσουγιάννη, Καθηγήτρια, Ιατρική, ΕΚΠΑ
Νικόλαος Ζίας, Πνευμονολόγος, Ναυτικό Νοσοκομείο Αθηνών
Νικόλαος Παπαδάτος, Αναπληρωτής Καθηγητής, Μαθηματικό, ΕΚΠΑ
Επιπολασμός του μεταβολικού συνδρόμου σε ασθενείς με σύνδρομο αποφρακτικης άπνοιας στον ύπνο
Prevalence of metabolic syndrome in patients with Obstructive Sleep Apnea Syndrome
Background: Obstructive Sleep Apnoea-Hypopnea syndrome (OSAHS) and Metabolic syndrome share common pathogenetic mechanisms such as central obesity, insulin resistance, dyslipidaemia, inflammation, and cardiovascular disease.
Objectives: In this cross-sectional, we aimed to investigate the variables that define OSAHS, including the metabolic syndrome, to patients which referred to the Sleep Laboratory of the Department of Pneumonology of the Naval Hospital of Athens (N.N.A.) for breath disorders during sleep.
Population and Method: Seventy-nine (63) subjects were studied, with medical history, clinical examination, laboratory biochemical tests and full polysomnography, from February 2011 until March 2012.
Results: Nineteen subjects (30,2%) did not suffer from OSAHS and served as controls, while 44 subjects (69,8%) suffered from mild (n=19), moderate (n=9) or severe (n=19) OSAHS. In the control group 7/19 subjects (36.84%) met the diagnostic criteria for metabolic syndrome. In the OSAHS group, 6/9 patients (66.67%) with mild disease, 7/16 patients (43.75%) with moderate disease and 7/19 patients (36.84%) with severe disease suffered from metabolic syndrome. No statistically significant difference in the prevalence of metabolic syndrome was detected between the groups.
Conclusions: The prevalence of metabolic syndrome, although high in patients with OSAHS, did not differ significantly from that in subjects without OSAHS.
Main subject category:
Obstructive Sleep Apnea Syndrome, Sleep, Sleep disorders, Metabolic syndrome
Number of references:
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