Κατεύθυνση Παθολογία της Κύησης
Library of the School of Health Sciences

2012-07-04

2012

Σπανού Φανή

Καθ. Εμμ. Σαλαμαλέκης (επιβλέπων), Καθ. Δημήτριος Κασσάνος, Αναπλ. Καθ. Κων. Λόγης

Αιμοσφαιρινoπάθειες και κύηση

Greek

Hemonoglobinopathies are a diverse group of inherited disorders of hemoglobin
production and function. They represent the most common single-gene disorders
that are found in humans and are distributed in various frequencies throughout
the world. In general, hemonoglobinopathies can be classified broadly as
disorders that result from structurally altered hemoglobin molecules (eg,
sickle cell anemia) or disorders that arise from numerical imbalance of
otherwise normal globin chain synthesis (eg, β-thalassemia). Recent advances in
the treatment of these disorders have increased the life span and quality of
life of affected individuals. It is increasingly common for women who are
affected with hemoglobinopathies to reach childbearing age and to desire
pregnancy. The unique physiologic changes of pregnancy may influence the mother’
s clinical condition significantly. In addition, the genetic nature of these
conditions raises special consideration in obstetrics for affected women and
their babies. These women require specialized multidisciplinary team management
pre-conception and throughout pregnancy. Timely screening programs must be in
place to identify women and their partners who are carriers of these conditions
and couples who are at risk for having an infant affected with a major
hemoglobinopathy.

Hemoglobinopathies, Pregnancy, Sickle cell disease, Thalassemias, Blood transfusions in hemoglobinopathies

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https://pergamos.lib.uoa.gr/uoa/dl/object/1309879