Retrospective analysis of smoking cessation in patients with cancer\;the experience of an outpatient clinic

Postgraduate Thesis uoadl:1309960 304 Read counter

Unit:
Κατεύθυνση Καρκίνος Πνεύμονα: Σύγχρονη Κλινικοεργαστηριακή Προσέγγιση και Έρευνα
Library of the School of Health Sciences
Deposit date:
2015-07-17
Year:
2015
Author:
Φλώρου Αγγελική
Supervisors info:
Καθηγήτρια Γκράτζιου Χριστίνα - Γεωργία
Original Title:
Αναδρομική καταγραφή διακοπής καπνίσματος σε ασθενείς με καρκίνο:η εμπειρία ενός εξωτερικού ιατρείου
Languages:
Greek
Translated title:
Retrospective analysis of smoking cessation in patients with cancer\;the experience of an outpatient clinic
Summary:
Introduction:
Smoking cessation after diagnosis of cancer improves efficacy of anticancer
treatment and quality of life while continuing smoking is associated with
poorer survival and increased risk for second primary tumors. Nevertheless,
almost half of patients continue to smoke after a diagnosis of cancer.
Aim:
The retrospective analysis of smoking cessation success and the assessment of
factors affecting success in a group of smokers with a history of cancer in the
context of an outpatient clinic.
Method:
We examined 1020 smokers, 83 with a history of various types of cancer and 937
without cancer. All smokers attended a 12 weeks program based on personal
counselling and first line pharmacological treatment against nicotine
dependence. Abstinence from smoking was confirmed by measuring exhaled CO.
Results:
The Continuous Abstinence Rate (CAR) among cancer patients was 55.47% and in
non-cancer patients was 67.02% and this difference was statistically
significant (p= 0.032). Sex and educational level did not affect the success of
cessation. The existence of a severe dependence is associated with poorer
outcomes in smoking cessation throughout the study population (p< 0.001) but
this does not apply to the group of cancer patients. Logistic regression
analysis showed that cancer is not a statistically significant factor at level
5% of significance, for smoking cessation success. The odds ratio for failure
in smoking cessation in cancer patients was 1.523 but the result is not
statistically significant at the 5% level (OR: 1.523 CI [0.957 2.424]
p=0.076]). The marginal probability effect of the cancer variable was 0.098 (CI
95% [-0.014 0.211], p=0.087) which means that the probability of failure in
quitting smoking in individuals with cancer increased by 9.8%.
Conclusions:
Smoking cessation in patients with cancer is accompanied by significant
success, although this outcome is poorer compared with non-cancer smokers. The
cessation rates could increase with early intervention through well-organized
smoking cessation programs
Keywords:
Smoking cessation, Cancer, Retrospective analysis, Outpatient clinic, Continouous abstinence
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
85
Number of pages:
107
File:
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