Κατεύθυνση Κλινική Παιδιατρική & Νοσηλευτική - Έρευνα
Library of the School of Health Sciences

2013-02-25

2013

Γιαννούλη Γεωργία

Χ. Τζουμάκα-Μπακούλα Καθηγήτρια Παιδιατρικής, Αθ. Μίχος Επίκουρος Καθηγητής Παιδιατρικής, Ε. Κυρίτση Καθηγήτρια Παιδιατρικής

Επιδημιολογία και κλινικά χαρακτηριστικά την Ν. Kawasaki στα Ελληνόπουλα

Greek

Epidemiology and clinical features of Kawasaki Disease in Greek children.

Objective: To describe epidemiology, clinical course and complications of
Kawasaki Disease (KD) in Greek children.
Methods: Medical records of children discharged with KD from a Tertiary
Pediatric hospital, during a decade (2001-2010) were retrospectively analyzed.
Results: Our study population consisted of 86 children <14 years of age (78% <5
years). Male/female ratio was 1.5:1, mean age 36.1 (SD=31.3) months and most of
admissions were between late autumn and spring. Incidence of KD was found
38.2/100.000 hospitalized children <14 years. Complete diagnostic criteria were
fulfilled in 64 children (74.4%), while 25.6% were considered as incomplete
cases. The mean duration of febrile disease was 9.5 (SD=3.2) days and the mean
duration of hospitalization 11.3 (SD=4.6) days. All children received
intravenous immunoglobulin (IVIG), while 25.6% required an additional dose.
Prevalence of the major clinical criteria of KD was significantly lower in the
subgroup of incomplete cases. Cardiovascular complications were detected in 48
children (55.8%) and coronary artery abnormalities (CAA) in 28 (32.6%)
(Complete: 42.2%, incomplete: 4.5%, P=0.001). Logistic regression analysis
showed that erythema in lips and oral cavity was positively associated with the
development of CAA (OR: 3.03, P value=0.040). Conversely, children with
incomplete KD (OR: 0.092, P value=0.032) and previous antibiotic treatment (OR:
0.17, P value=0.034) were less likely to develop CAA.
Conclusions: In our study population, children with incomplete presentation of
KD or previous antibiotic treatment were in significantly lower risk to develop
CAA.

Kawasaki disease, Epidemiology, Incomplet Kawasaki disease, Treatment, Coronary artery abnormalities

No

0

No

236

128

File access is restricted only to the intranet of UoA.

https://pergamos.lib.uoa.gr/uoa/dl/object/1311172