Κατεύθυνση Καρκίνος Πνεύμονα: Σύγχρονη Κλινικοεργαστηριακή Προσέγγιση και Έρευνα
Library of the School of Health Sciences

2014-07-18

2014

Ρεβελιώτης Κωνσταντίνος

Kωνσταντίνος Ν. Συρίγος

Χειρουργική θεραπεία όγκων μεσοθωρακίου σε παιδιά και εφήβους: αναδρομική μελέτη

Greek

Surgical treatment of mediastinal neoplasms in children and adolescents: a retrospective review

Introduction: Tumors of mediastinum in children are relatively uncommon tumors
of diverse histology and location.
Objective: Purpose of this paper is the retrospective study of all cases of
mediastinal tumors in children that underwent any kind of surgical intervention
between the years 2002-2010 at a single institution (single-institution
analysis) and the report of their features with regard to age, sex, clinical
presentation, location, diagnostic work-up, surgical treatment, histology,
postoperative complications, adjuvant therapy, disease-free and overall
survival.
Method: Retrospective collection of all scientific data from the medical files
of 34 young patients with tumors of mediastinum.Discussion of the results.
Outcomes: 36 primary tumors of the mediastinum were found: 16 benign (44.4%)
and 20 malignant (55.6%). The age of the patients was ranging from 9 days up to
15,5 years with a mean age that of 5.9 years. 6 children were asymptomatic on
diagnosis, but the rest 28 were presented with symptoms. Regarding pathology,
12 tumors were of neurogenic origin, 5 were lymphomas, 8 thymic tumors, 3
non-seminomatous germ cell tumors, 2 mesenchymal tumors and 6 mediastinal
cysts. Regarding the type of surgical intervention 29 children underwent
radical or partial resection of the mass and the rest 5 children had an open
biopsy. The most common postoperative complications were Horner’s syndrome and
paralysis of ipsilateral hemidiaphragm. Intraoperative and early postoperative
mortality were zero. 19 children with malignant tumors had chemo(radio)therapy
as a (neo)adjuvant treatment. Relapse of cancer emerged in 3 children, while
four in total remained with residual masses until the end. All children are
alive.
Conclusion: Primary mediastinal tumors in children differ from those in adults
in regard with both their histology and clinical presentation.

Μediastinal neoplasms, Children, Surgical treatment, Mediastinal tumors, Review

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https://pergamos.lib.uoa.gr/uoa/dl/object/1314505