Unit:
Speciality Clinical NeuropsychologyLibrary of the School of Health Sciences
Supervisors info:
Αναπληρωτής καθηγητής νευρολογίας και νευροψυχολογίας Σωκράτης Γ. Παπαγεωργίου
Original Title:
Idiopathic rem sleep behavior disorder and driving performance
Translated title:
Ιδιοπαθής διαταραχή της συμπεριφοράς του ύπνου ρεμ και οδηγική συμπεριφορά
Summary:
Rem Sleep Behavior Disorder (RBD) is a uniquely interesting sleep disorder
which may represent the prodromal phase mostly of a-synucleinopathies and
rarely taupathies and amyloidopathies. For the time being its significance is
confined to the disruption of sleep however, research attention is shifting to
its correlation with the neurodegenerative disorders and the possibility to be
accounted for, as an early marker. There is limited literature data concerning
the neuropsychological profile of iRBD and none concerning their daily
functionality. The objective of this research is multidimensional; a) to
investigate the neuropsychological profile of Greek iRBD patients b) to
analyze the driving performance of iRBD patients compared to healthy subjects
as one aspect of everyday life and c) test the hypothesis that iRBD
neuropsychological scores can predict deficient driving. Methodology: The
experiment was carried out at the simulator of the National Technical
University of Athens, in which all participants after a thorough neurological
and neuropsychological assessment were asked to drive under different types of
road (rural/ urban) and distraction (no distraction, conversation, mobile
use).iRBD population has impaired performance in neuropsychological testing.
Their abnormal neuropsychological scores seems to extend in everyday
functionality specifically their driving performance. Neuropsychological tasks
of semantic fluency and LNS can predict deficient driving.
Keywords:
Idiopathic rem sleep behavior disorder, Driving, Neuropsychological profile, Functionality, A-synucleinopathies
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