Unit:
Κατεύθυνση Κλινική ΧημείαLibrary of the School of Science
Author:
Νανόπουλος Κωνσταντίνος
Supervisors info:
Λιανίδου Ευρύκλεια Καθηγήτρια (Επιβλέπουσα), Κουππάρης Μιχαήλ Καθηγητής, Μουτσάτσου Παρασκευή Καθηγήτρια
Original Title:
Ανάπτυξη και επικύρωση θολοσιμετρικής μεθόδου για την μέτρηση της συστατίνης C στα ανθρώπινα ούρα σε αυτόματο βιοχημικό αναλύτη
Translated title:
Measurment of cystatin C in human urine by particle-enhanced turbidimetric immunoassay on an automated biochemistry analyzer
Summary:
Cystatin C (CysC), is produced by all nucleated cells of human body, is freely
filtered by the kidney glomerulus and reabsorbed by the tubules. It is widely
accepted that no tubular secretion of CysC occurs. Raised urinary levels are
believed to indicate tubular damage.
We report here the validation of a quantitative assay to measure urinary
cystatin C (uCysC) using a commercial CysC kit based on a latex
particle-enhanced turbidimetric immunoassay (PETIA), on an automated
biochemistry analyzer. The clinical relevance of this assay was tested on
several kidney disease patients and a reference range was determined using
healthy controls.
Keywords:
Petia, Cystatin C, Aki, Kidney Biomarkers, Kidney Damage
Number of references:
181
File:
File access is restricted.
document.pdf
4 MB
File access is restricted.
