Development and validation of determination of Clioquinol and impurities in ointment formulation

Postgraduate Thesis uoadl:1316005 224 Read counter

Unit:
Κατεύθυνση Έλεγχος Φαρμακευτικών Ενώσεων (Φαρμακευτική Ανάλυση)
Library of the School of Science
Deposit date:
2013-07-19
Year:
2013
Author:
Φαναρά Ευαγγελία
Supervisors info:
Μιχαήλ Κουππάρης Καθηγητής
Original Title:
Ανάπτυξη και επικύρωση μεθόδων προσδιορισμού κλιοκινόλης και των προσμίξεων της σε σκεύασμα αλοιφής
Languages:
Greek
Translated title:
Development and validation of determination of Clioquinol and impurities in ointment formulation
Summary:
The formulation used was an antifungal ointment which contained 3% of
Clioquinol and 0.025% Fluocinolone. Several tests resulted to the best
chromatographic conditions. In addition, for the validation were carried out
controls of selectivity, accuracy, linearity, precision, robustness and
stability. The methods developed were practical so that could be easily used in
busy analytical laboratories.
Keywords:
HPLC, Clioquinol, Ointment, Validation, Analytical method
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
23
Number of pages:
118
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