Bioinformatic analysis of the HU protein family

Postgraduate Thesis uoadl:2815629 70 Read counter

Unit:
Κατεύθυνση Βιοπληροφορική
Library of the School of Science
Deposit date:
2018-11-22
Year:
2018
Author:
Antonogiannakis Dimitris
Supervisors info:
Κωνσταντίνος Βοργίας, Καθηγητής, Μοριακή Βιολογία και Βιοχημεία, ΕΚΠΑ
Original Title:
Βιοπληροφορική ανάλυση της οικογένειας των πρωτεινών HU
Languages:
Greek
Translated title:
Bioinformatic analysis of the HU protein family
Summary:
The histone-like (HU) protein is one of the major protein of the bacterial nucleoid. Here we bioinformatically approach the analysis of the HU family. First, we build homo/ hetero dimer models through the Homology Modelling and then we evaluated their structure. Then we locate the Dimerisation Signal (DS) and it correlated with the structural stability. Finally, we execute comparative analysis of interatomic interactions between of the HU models and we correlated them with the Growth Optimal Temperature (GOT) of the organisms in which these proteins expressed.
Main subject category:
Science
Keywords:
HU protein, Dimerisation Signal, DS, Growth Optimal Temperature, GOT, interatomic interactions, Homology Modelling,
Index:
No
Number of index pages:
0
Contains images:
No
Number of references:
67
Number of pages:
131
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