Κατεύθυνση ΒιοπληροφορικήLibrary of the School of Science
Κωνσταντίνος Βοργίας, Καθηγητής, Μοριακή Βιολογία και Βιοχημεία, ΕΚΠΑ
Βιοπληροφορική ανάλυση της οικογένειας των πρωτεινών HU
Bioinformatic analysis of the HU protein family
The histone-like (HU) protein is one of the major protein of the bacterial nucleoid. Here we bioinformatically approach the analysis of the HU family. First, we build homo/ hetero dimer models through the Homology Modelling and then we evaluated their structure. Then we locate the Dimerisation Signal (DS) and it correlated with the structural stability. Finally, we execute comparative analysis of interatomic interactions between of the HU models and we correlated them with the Growth Optimal Temperature (GOT) of the organisms in which these proteins expressed.
Main subject category:
HU protein, Dimerisation Signal, DS, Growth Optimal Temperature, GOT, interatomic interactions, Homology Modelling,