Unit:
Τομέας ΠαθολογίαςLibrary of the School of Health Sciences
Dissertation committee:
Κουλούρης Νικόλαος, Καθηγητής, Ιατρική, ΕΚΠΑ
Ζακυνθινός Σπυρίδων, Καθηγητής, Ιατρική, ΕΚΠΑ
Κουτσούκου Αντωνία, Καθηγήτρια,Ιατρική,ΕΚΠΑ
Μπακάκος Πέτρος, Αναπλ. Καθηγητής, Ιατρική, ΕΚΠΑ
Στρατάκος Γρηγόριος, Αναπλ. Καθηγητής, Ιατρική, ΕΚΠΑ
Ροβίνα Νικολέττα, Επικ. Καθηγήτρια, Ιατρική, ΕΚΠΑ
Βασιλειάδης Ιωάννης, Επικ. Καθηγητής, Ιατρική, ΕΚΠΑ
Original Title:
Εξισώσεις πρόβλεψης φυσιολογικών σπιρομετρικών τιμών και η χρησιμότητα τους στον διαχωρισμό των αποφρακτικών ασθενών
Translated title:
Spirometric values of greek people and comparison with ECSCand GLI values in COPD people
Summary:
Background:
During the past few years, the use of criteria introduced by Global Initiative for Chronic Obstructive Lung Disease (GOLD) are introduced for the diagnosis and classification of Chronic Obstructive Pulmonary Disease(COPD),taking into account the values of a forced expiratory volume in 1 second (FEV1) and a forced expiratory volume in 1 second (FEV1) to forced vital capacity (FVC) ratio (FEV1/FVC%). In Europe, the reference values of the European Coal and Steel Community (ECSC), that were originally developed in 1983, are still used.
Aim of the Study:
The study aimed to carry out measurement of spirometric values in a healthy, non smoking Greek population, development of local equations and comparison with ECSC and Global Lung Initiative(GLI) equations, in order to see if there is a need for separate ones in everyday use for the classification of patient with COPD.
Methods:
Normal predicted values for FEV1 and FEV1/FVC% were obtained from a group of 500 healthy subjects, aged 18-89 years. In addition, a group of 124 COPD patients, with no other comorbidities was studied. Patients were classified according to GOLD criteria in four groups with ECSC, GLI predicted values or with our own predicted values.
Results:
The statistical analysis has revealed that there is no significant difference among the three sets of predicted values and no significant statistical difference was detected among the classification of COPD patients.
Conclusion: It is shown that the 3 sets of predicted values are almost identical, despite the fact that they have been collected from different study populations. Αccording to the study, there is no need in recalculating values for Greek population.
Main subject category:
Health Sciences
Keywords:
Spirometric values, Greek people, Comparison
Number of references:
104
