Unit:
Κατεύθυνση Οργανική Σύνθεση και Εφαρμογές της στη Χημική ΒιομηχανίαLibrary of the School of Science
Author:
Tzaras Dimitrios-Ioannis
Supervisors info:
Κοκοτός, Χριστόφορος, Επίκουρος Καθηγητής, ΕΚΠΑ
Κοκοτός, Γεώργιος, Καθηγητής ΕΚΠΑ
Βασιλείου Σταματία, Επίκουρη Καθηγήτρια ΕΚΠΑ
Original Title:
Ανάπτυξη καινοτόμων καταλυτικών μετασχηματισμών φιλικών προς το περιβάλλον
Translated title:
Development of innovative and enviromentally friendly catalytic transformations
Summary:
Organocatalysis constitutes a new and fast moving catalysis’ field, which offers the opportunity of utilizing catalysts of low cost and environmentally friendly conditions in order to achieve a variety of asymmetric reactions. The first chapter of this thesis presents an introduction in Organocatalysis and refers to a literature survey regarding the organocatalytic Diels-Alder reaction. The second chapter presents examples on the organocatalytic epoxidation of alkenes and a review οn the organocatalytic oxidation method, which was developed in the Laboratory of Organic Chemistry of the Department of Chemistry of the National and Kapodistrian University of Athens. The third chapter presents the basic principles of Organometallic Chemistry and refers to a literature survey regarding the use of palladium in Organic Synthesis. Photocatalysis is a new, interesting field which focuses on the use of irradiation as a source of energy. The fourth chapter of this thesis presents an introduction in Photochemistry and its applications in the photocatalytic oxidation of alcohols. The fifth chapter presents the aim of this thesis. The sixth chapter presents the synthesis of unsaturated alcohols for the asymmetric organocatalytic Diels-Alder reaction and the separation of the products of the above mentioned reaction through HPLC utilizing chiral columns for the determination of the enantiomeric purity. The seventh chapter studies the synthesis of proline-based compounds and their study as organocatalysts for the asymmetric epoxidation of alkenes. The eighth chapter presents the synthesis of substituted benzofurans and indoles utilizing Pd/C as the promoter and studies regarding the recycling and reuse of the catalyst.
Main subject category:
Science
Keywords:
Organocatalysis, Photocatalysis, Diels-Alder reaction, Epoxidation of alkenes, Heterocyclic compounds, Oxidation of alcohols.
Number of references:
176
