Τομέας Χειρουργικής
Library of the School of Health Sciences

2019

2018

Karmiris Efthymios

Αποστολόπουλος Μιχαήλ, Καθηγητής, Ιατρική, ΕΚΠΑ
Κουτσανδρέα Χρυσάνθη, Καθηγήτρια, Ιατρική, ΕΚΠΑ
Παπακωνσταντίνου Δημήτριος, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Μπρούζας Δημήτριος, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Γεωργάλας Ηλίας, Αναπληρωτής Καθηγητής, Ιατρική, ΕΚΠΑ
Χατζηστεφάνου Κλειώ, Αναπληρώτρια Καθηγήτρια, Ιατρική, ΕΚΠΑ
Δρούτσας Κωνσταντίνος, Επίκουρος Καθηγητής, Ιατρική, ΕΚΠΑ

Συγκέντρωση TGF και Μεταλλοπρωτεϊνασών στον ορό αίματος ασθενών με χρόνιο απλό και ψευδοαποφολιδωτικό γλαύκωμα

Greek

TGF and matrix metalloproteinases in blood serum and their role in primary open angle glaucoma and pseudoexfoliation glaucoma

Purpose: The purpose of the study was to identify any potential association between the single nucleotide polymorphism rs1800470 (869Τ/C) located at in exon 1 which can lead to a leucine-to-proline substitution at codon 10, and Primary Open Angle Glaucoma.
Methods: One hundred and fourteen Open Angle Glaucoma cases and a control group of 138 healthy cases were recruited from the 1st Ophthalmology Department of Athens University. DNA was isolated from whole blood samples and genotype frequencies for the polymorphism rs1800470 (869Τ/C) of the TGF-β1 gene were assessed.
Results: No significant differences in genotype distribution frequencies for the polymorphism rs1800470 (869Τ/C) of the TGF-β1 gene could be established between patients with POAG and control subjects.
Conclusions: The present study failed to find any significant genotypic association with POAG.

Health Sciences

Matrix metalloproteinases, TGF, Primary open angle glaucoma

No

0

Yes

149

112

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https://pergamos.lib.uoa.gr/uoa/dl/object/2885238