Τhe correlation between the clinical features, the differential diagnosis and the final histopathologic diagnosis concerning the Oral Squamous Cell Carcinoma.

Postgraduate Thesis uoadl:2887220 197 Read counter

Unit:
Κατεύθυνση Οδοντοφατνιακή Χειρουργική
Βιβλιοθήκη Οδοντιατρικής
Deposit date:
2020-02-02
Year:
2019
Author:
Kapopoulou Faidra
Supervisors info:
Χριστόπουλος Παναγιώτης, Επίκουρος Καθηγητής, Τμήμα Οδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ.
Θεολόγη - Λυγιδάκη Κωνσταντίνα, Επίκουρη Καθηγήτρια, Τμήμα Οδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ.
Τόσιος Κωνσταντίνος, Αναπληρωτής Καθηγητής, Τμήμα Οδοντιατρικής, Σχολή Επιστημών Υγείας, ΕΚΠΑ.
Original Title:
Συσχέτιση της κλινικής εικόνας με τη διαφορική διάγνωση και την τελική ιστοπαθολογική διάγνωση όσον αφορά στο Ακανθοκυτταρικό Καρκίνωμα του Στόματος
Languages:
Greek
Translated title:
Τhe correlation between the clinical features, the differential diagnosis and the final histopathologic diagnosis concerning the Oral Squamous Cell Carcinoma.
Summary:
Introduction: Oral cancer represents the eighth most common malignancy of the human body, and the most frequent malignancy of the oral cavity is squamous cell carcinoma. The five-year survival rates are under 60%. Tobacco, alcohol consumption and HPV- infection are the most determinant risk factors, especially when acting synergistically. Oral SCC can be presented with many different clinicopathological features, especially during the early stages and thus it is very difficult to be diagnosed. Different diagnostic methods have been proposed, but doctor’s knowledge and discernment still remains the golden standard.
Aim: To investigate the correlation between the clinical features, the differential diagnosis and the final histopathologic diagnosis concerning the Oral Squamous Cell Carcinoma.
Materials and methods: This is a retrospective clinocostatistic study for the period of 1992- 2015. All the cases were collected from the department of Oral Pathology and Medicine of Athens Dental School and they were divided in two groups. Group A ( 412 cases ) included all the cases with a final histopathlogical diagnosis of OSCC, whereas Group B ( 514 ) was formed with cases in which the attending doctor had included the OSCC in the differential diagnosis. The cases that complied with the inclusion criteria of our study in both teams simultaneously, they were included in each group and studied independently.
Results: The mean age of all patients as well as the male : female ratio were very similar for both groups. For group A the male rate was 52, 2% and for group B 49,8% accordingly. The most frequent clinical characteristic was the presence of an ulcer (45%). The border of the tongue was the most common affected location of OSCC (40%) and the buccal mucosa was following with 11-12%. There was a clear prominence of specialized doctors in recognizing the type of the lesion in the oral mucosa and performing a biopsy.
Conclusion: General dentists have to be thoroughly informed regarding the consequences, prevention and diagnosis of OSCC’s.
Main subject category:
Health Sciences
Keywords:
OSCC, Ulcer, Risk factors, Diagnosis
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
97
Number of pages:
103
File:
File access is restricted only to the intranet of UoA.

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