Supervisors info:
Λαμπροπούλου Δήμητρα, Αναπληρώτρια Καθηγήτρια, Εργαστήριο Ελέγχου Ρύπανσης Περιβάλλοντος, Τομέας Φυσικής, Αναλυτικής και Περιβαλλοντικής Χημείας, Τμήμα Χημείας, Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης
Summary:
This study reports an analytical method for the determination of residues of pesticides using liquid chromatography mass spectrometry (LC-MS). A modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) methodology was used to extract the analytes and determine different groups of pesticides in soil samples by LC-MS. Optimization of the method was performed by studding parameters affecting QuEChERS in both extraction/partitioning and clean up steps. Different extraction solvents, amounts and combinations of salts as well as clean-up sorbents (C18, GCB, PSA, Florisil) were investigated and compared. Finally, the optimized method was validated by evaluating the linearity, accuracy, precision (repeatability, reproducibility), method detection and quantification limits (LODs, LOQs) according το SANTE/11813/2017 guidelines.
Keywords:
QuEChERS, pesticides, soil, multi-residue method, LC-MS
