Speciality Clinical Neuropsychology
Library of the School of Health Sciences

2020-07-19

2020

Palioura Sofia

Κωνσταντίνος Πόταγας, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Νικόλαος Σμυρνής, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Σωκράτης Παπαγεωργίου, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ

Η φύση των οσφρητικών διαταραχών στη νόσο του Parkinson

Greek

The nature of olfactory disorders in Parkinson's disease

Olfactory disorders appear as an early symptom in a large percentage of patients with Parkinson's disease and are a useful clinical indicator for the diagnosis of the disease. The aim of the study is to determine the exact olfactory deficit presented by people with Parkinson's disease by evaluating the stages of olfactory stimulus processing. The hypothesis is that the deficit concerns the processing of olfactory stimuli to a higher level of cognition. Twenty-six patients in the early stages of the disease from the Special Clinics for Extrapyramidal Diseases of the First Neurological Clinic of NKUA, at the Eginition Hospital, and 26 healthy controls of the same age and cultural environment were examined. Demographics and clinical history were recorded, a brief neuropsychological assessment of mental functions was performed, and four supernatural olfactory stimuli tests were administered. The tests involve different stages of olfactory processing: perception and retention of stimuli, for immediate recognition and discrimination, without recognition or nominal identification (perceptual stage), and identification of stimuli through verbal cues (superior processing stage). The total duration of the examination is 30 minutes. The performance of patients with Parkinson's disease was found to be worse than that of healthy controls in both perceptual and superior processing of olfactory stimuli. However, the repeated measures ANOVA within the groups showed a significant difference in performance between the perception and superior processing tests, but only in the patient group. There is therefore evidence of "olfactory agnosia" in patients with Parkinson's disease.

Health Sciences

Parkinson, Olfactory, Agnosia

No

0

Yes

40

22

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https://pergamos.lib.uoa.gr/uoa/dl/object/2919813