Κατεύθυνση Βιοπληροφορική
Library of the School of Science

2020-09-16

2020

Tzanos Dimitrios

Αλέξανδρος Γ. Γεωργακίλας, Αναπληρωτής Καθηγητής, Σχολή Εφαρμοσμένων Μαθηματικών και Φυσικών Επιστημών, Εθνικό Μετσόβιο Πολυτεχνείο
Κωνσταντίνος Ε. Βοργιάς, Καθηγητής, Τμήμα Βιολογίας, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών
Βασιλική Α. Οικονομίδου, Επίκουρη Καθηγήτρια, Τμήμα Βιολογίας, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών

Ανάλυση Μικροσυστοιχιών σε Καρκινικά Βλαστικά Κύτταρα

Greek

Analysis of Microarray Data in Cancer Stem Cells

"Cancer stem cell" is a generic term referring to cancer cells capable of differentiation and self-renewal, which are seemingly the main reason for can-cer stem cell resistance to chemotherapy. Their origin remains unclarified, although a number of assumptions have been proposed. Cancer stem cells play a key role in the development, metastasis, and recurrence of cancer.
The purpose of the present study is to use gene expression data from a va-riety of cancer stem cell tissues to determine the mechanisms of patho-genicity and response in therapeutic regimens. Statistical analysis and functional analysis of the data are performed and a method of comparative study and correlation of the resulting models based on a nodal phenotype is developed.

Science

microarrays, cancer stem cells, pan-cancer gene tag

Yes

3

Yes

184

190

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https://pergamos.lib.uoa.gr/uoa/dl/object/2922601