Unit:
Κατεύθυνση Οργανική Σύνθεση και Εφαρμογές της στη Χημική ΒιομηχανίαLibrary of the School of Science
Supervisors info:
Χριστόφορος Κόκοτος, Αναπληρωτής Καθηγητής, Τμήμα Χημείας, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών
Original Title:
Σύνθεση Υδροξαμικών Οξέων και Μελέτη τους ως Καταλυτών σε Αντιδράσεις Οργανοκαταλυτικής Οξείδωσης
Translated title:
Synthesis of Hydroxamic Acids and their Study as Catalysts in Organocatalytic Oxidation Reactions
Summary:
Organocatalysis is a new and rapidly developing field of Organic Catalysis, which is depending on the use of small organic molecules to catalyze organic reactions. In this thesis, in chapter one, general information about the field of Organocatalysis is presented, as well as a thorough report on organocatalytic oxidation of alkenes (Chapter 1) and silanes (Chapter 2) based on literature. Moreover, the use of hydroxamic acids in the catalysis field is described (Chapter 1).
In chapter 3, the main goals of this thesis are presented:
The design and synthesis of hydroxamic acid derivatives, in order to study their catalytic action in epoxidation reactions (Chapter 4) and oxidation of silanes (Chapter 5), utilizing H2O2 as the green oxidant and
The mechanistic studies that were carried out via High Resolution Mass Spectroscopy (HRMS), as described in chapter 4.
Finally, in chapter 6 the experimental procedure and the characterization of all synthesized substances, are provided.
Main subject category:
Science
Keywords:
Organocatalysis, epoxidation, oxidation of silanes, hydroxamic acids, green chemistry.
Number of references:
118
