Investigating the structure and white matter fiber tracts of the precuneus: implications in approaches to the lateral ventricle

Doctoral Dissertation uoadl:2931753 196 Read counter

Unit:
Faculty of Medicine
Library of the School of Health Sciences
Deposit date:
2020-12-28
Year:
2020
Author:
Skandalakis Georgios
Dissertation committee:
Θεόδωρος Τρουπής, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Χρήστος Μαρκόπουλος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Γεώργιος Στράντζαλης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Βασίλειος Πρωτογέρου, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Μαρία Πιάγκου, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Δημήτριος Βλαχοδημητρόπουλος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Νικόλαος Γούτας, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Μελέτη της δομής και των δεματίων της λευκής ουσίας του προσφηνοειδούς λοβίου: Η σχέση τους στις προσπελάσεις του τριγώνου της πλάγιας κοιλίας
Languages:
English
Translated title:
Investigating the structure and white matter fiber tracts of the precuneus: implications in approaches to the lateral ventricle
Summary:
The anatomy of the human precuneus exhibits significant variability and has remained one of the less accurately mapped areas of the human brain. Although the functional connectivity of the precuneus and its significance have been repeatedly reported, the underlying structural circuit has not been characterized. Understanding the underlying structural connectivity of these networks is critical for refining their circuitry, clarifying their function and implementing safe neurosurgical approaches. The aim of this dissertation was to investigate the surface anatomy and fiber tracts of the precuneal region in cadaveric specimens. By mapping the sulcal anatomy of the precuneus and employing the fiber microdissection technique, we demonstrate the variations of the Subparietal sulcus (SpS) and the parietooccipital sulcus (POS) and the anatomy and connectivity of the Sledge Runner Fasciculus (SRF), dorsal component of the superior longitudinal fasciculus (SLF- 1), middle longitudinal fasciculus (Mdlf), inferior fronto-occipital fasciculus (IFOF), claustrocortical fibers and fifth component of the cingulum bundle (CB-V). We found the Precuneus surface anatomy to be considerably variable. We also found The MdLF-I, connecting the dorsolateral Temporal Pole and STG to the precuneus; SRF not to participate in the connectivity of the precuneus but connecting the cortical areas of the anterior cuneus, anterior lingula, isthmus of the cingulum and posterior parahippocampal gyrus; SLF- 1 connecting the precuneus with areas of the medial frontal lobe ; the IFOF connecting the precuneus with the frontal lobe; claustrocortical fibers connecting the precuneus with the claustrum and The CB-V connecting the precuneus with the regions of the temporal lobe.
Main subject category:
Health Sciences
Keywords:
Brain connectivity, Fiber tracts, White matter, Neuroanatomy, Parietal lobe, Precuneus
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
234
Number of pages:
178
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