Unit:
Κατεύθυνση Έρευνα στην Γυναικεία ΑναπαραγωγήLibrary of the School of Health Sciences
Author:
Sakali Anastasia-Konstantina
Supervisors info:
Γεώργιος Μαστοράκος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Αλεξάνδρα Μπαργιώτα, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, Πανεπιστήμιο Θεσσαλίας
Μαρία Παπαγιάννη, Επίκουρος Καθηγήτρια, Τμήμα Διαιτολογίας και Διατροφολογίας, Πανεπιστήμιο Θεσσαλίας
Original Title:
Η επίδραση των περιβαλλοντικών παραγόντων στη γυναικεία γονιμότητα και στην κύηση, με έμφαση στο ρόλο των Ενδοκρινικών Διαταρακτών
Translated title:
Influence of environmental factors on female fertility and pregnancy, with a focus on the interference of endocrine disruptors
Summary:
Over the recent years, female fertility problems and number of pregnancies resulting into negative outcomes have been on the rise becoming a matter of particular concern among women of childbearing age. The rise in the above adverse reproductive health outcomes could be partly attributed to the exposure to hazardous factors ubiquitously found in the environment. To investigate this hypothesis, in this chapter we summarize the current evidence on the impact of environmental factors and endocrine disruptors (EDs) on female fertility (either non-assisted or assisted) and on pregnancy outcomes (ectopic pregnancy, pregnancy losses, gestational diabetes, hypertensive disorders of pregnancy, preterm birth, intrauterine growth restriction, small and large for gestational age, birth defects). Because it has been established that environmental factors and EDs are capable to induce epigenetic alterations, special care has been given to the exploration of their transgenerational effects on female fertility and pregnancy outcomes.
Main subject category:
Health Sciences
Keywords:
Environmental factors, Endocrine disruptors, Female fertility, Pregnancy outcomes, Reproduction, In vitro fertilization
