Title:
Estimation of radiation dose and risk to children undergoing cardiac catheterization for the treatment of a congenital heart disease using Monte Carlo simulations
Languages of Item:
English
Abstract:
Background: Children diagnosed with congenital heart disease often undergo cardiac catheterization for their treatment, which involves the use of ionizing radiation and therefore a risk of radiation-induced cancer. Objective: The purpose of this study was to calculate the effective and equivalent organ doses (HT) in those children and estimate the risk of exposure-induced death. Materials and methods: Fifty-three children were divided into three groups: atrial septal defect (ASD), ventricular septal defect (VSD) and patent ductus arteriosus (PDA). In all procedures, the exposure conditions and the dose-area product meters readings were recorded for each individual acquisition. Monte Carlo simulations were run using the PCXMC 2.0 code and mathematical phantoms simulating a child's anatomy. The HT values to all irradiated organs and the resulting E and risk of exposure-induced death values were calculated. Results: The average dose-area product values were, respectively, 40 ± 12 Gy·cm2 for the ASD, 17.5 ± 0.7 Gy·cm2 for the VSD and 9.5 ± 1 Gy·cm 2 for the PDA group. The average E values were 40 ± 12, 22 ± 2.5 and 17 ± 3.6 mSv for ASD, VSD and PDA groups, respectively. The respective estimated risk of exposure-induced death values per procedure were 0.109, 0.106 and 0.067%. Conclusion: Cardiac catheterizations in children involve a considerable risk for radiation-induced cancer that has to be further reduced. © 2012 Springer-Verlag.
Authors:
Yakoumakis, E.
Kostopoulou, H.
Makri, T.
Dimitriadis, A.
Georgiou, E.
Tsalafoutas, I.
Journal:
Pediatric Radiology
Publisher:
Springer-Verlag
Keywords:
article; bone marrow; breast; cardiovascular risk; child; childhood disease; congenital heart disease; dose response; heart; heart atrium septum defect; heart catheterization; heart ventricle septum defect; human; infant; liver; lung; major clinical study; Monte Carlo method; pancreas; patent ductus arteriosus; preschool child; priority journal; radiation dose; radiation exposure; radiation hazard; retrospective study; risk assessment; school child; skin; spleen; stomach; thymus; thyroid gland
Official URL (Publisher):
DOI:
10.1007/s00247-012-2510-3
