Title:
Indication of increased phase coupling between theta and gamma EEG
rhythms associated with the experience of auditory verbal hallucinations
Languages of Item:
English
Abstract:
Electroencephalographic oscillations, with different spectral contents,
recorded in various brain sites are assumed to play an important role in
the information processes underlying cognition as well as the abnormal
brain functioning observed in nosological entities that affect neuronal
connectivity such as schizophrenia. In the present study we investigated
the interaction of EEG rhythms during the experience of auditory verbal
hallucinations (AVHs). For this purpose we analyzed data obtained from
patients suffering from persistent AVHs, focusing on the mode that the
phase of theta oscillations modulate the amplitude of the broad gamma
EEG oscillations. Our results indicate increased phase coupling between
theta and gamma rhythms observed in the left frontotemporal cortices
during AVHs, under eyes closed condition. The average differences of
theta-gamma coupling between hallucinatory and resting stages in the
left temporal area were found to be statistically significant. These
results suggest that a theta-gamma interaction may be involved in the
production and experience of AVHs in patients suffering from
schizophrenia. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
Authors:
Koutsoukos, Elias
Angelopoulos, Elias
Maillis, Antonis and
Papadimitriou, George N.
Stefanis, Costas
Journal:
Neuroscience Letters
Publisher:
Elsevier Ireland Ltd
Keywords:
Auditory verbal hallucinations; EEG phase synchrony; Theta-gamma
coupling; Schizophrenia
Official URL (Publisher):
DOI:
10.1016/j.neulet.2012.12.005
