A meta-analysis of nocebo effect on double -blind randomized controlled trials on bisphosphonates .

Postgraduate Thesis uoadl:3228184 10 Read counter

Unit:
Κατεύθυνση Φυσιολογία της Γήρανσης και Γηριατρικά Σύνδρομα
Library of the School of Health Sciences
Deposit date:
2022-08-05
Year:
2022
Author:
Mouratidou Pelagia
Supervisors info:
Σφηκάκης Πέτρος, Καθηγητής , Ιατρική Σχολή, ΕΚΠΑ
Κραββαρίτη Ευριδίκη, Γηρίατρος - Ακαδημαϊκή Υπότροφος, Ιατρική Σχολή, ΕΚΠΑ
Γιαβροπούλου Μαρία, Ενδοκρινολόγος-Διευθύντρια ΕΣΥ, Α’ Προπαιδευτική Παθολογική Κλινική, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Μία μετά-ανάλυση του αποτελέσματος του nocebo σε τυχαιοποιημένες ελεγχόμενες μελέτες στα διφωσφονικά φάρμακα.
Languages:
Greek
Translated title:
A meta-analysis of nocebo effect on double -blind randomized controlled trials on bisphosphonates .
Summary:
In this systematic review and meta-analysis the investigetation guestion is the nocebo effect on the use of bisphosphonates through RCTs on primary osteoporosis.
An indirect indicator of nocebo is the measurement of the percentile of the population that quit the study claiming they developed side effects.
The conclusion of the trial is that 1 in 10 individual withdrew from the control group due to side effects from all biphosphonates
In addition individuals over 63 years old showed a higher incidence of side effects as compared to below that age group.
Main subject category:
Health Sciences
Keywords:
Nocebo, Osteoporosis, Bisphosphonates
Index:
Yes
Number of index pages:
2
Contains images:
Yes
Number of references:
53
Number of pages:
74
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