The role and mechanism of action of vitamin C and E in wound healing

Postgraduate Thesis uoadl:3327448 90 Read counter

Unit:
Κατεύθυνση Χειρουργική Νοσηλευτική
Library of the School of Health Sciences
Deposit date:
2023-05-10
Year:
2023
Author:
Lepidou Sonia
Supervisors info:
Ελένη Θεοδοσοπούλου, Καθηγήτρια, Τμήμα Νοσηλευτικής, ΕΚΠΑ
Ευάγγελος Κωνσταντίνου, Καθηγητής, Τμήμα Νοσηλευτικής, ΕΚΠΑ
Θεόδωρος Μαριόλης-Σαψάκος, Αναπληρωτής Καθηγητής, Τμήμα Νοσηλευτικής, ΕΚΠΑ
Original Title:
Ο ρόλος και ο μηχανισμός δράσης της βιταμίνης C και E στην επούλωση των τραυμάτων
Languages:
Greek
Translated title:
The role and mechanism of action of vitamin C and E in wound healing
Summary:
Aim: The main purpose of this study was to search and record as completely as possible all the available data regarding the role and mechanism of action of vitamins C and E.

Methodology: This research is a systemic review based on the study of recent scientific articles and research. Searches were carried out on PubMed, Google Scholar, and Scopus search engines, in the period between January and September 2022. The search included a combination of various terms (keywords) as well as a combination of these terms in the Greek and English languages, in order to identify and display articles that come as close as possible to the subject of the investigation.

Results: The use of vitamin C and E supplements, alone or combined, speeds up the process of healing in patients with pressure ulcer, diabetic ulcers as well as in cases after dental extraction. In addition, the use of local a-tocopherol and vitamin C can significantly reduce the wound size and enhance the process of healing in burn patients.

Conclusions: From this systemic review, it is concluded that the use of vitamin C and E, both systemically and locally, can have a positive effect on wound healing. In addition, given that most of the studies regarding vitamin E that were available, were mostly about rodents and they could not be extended to all patients, it is concluded that further studies should be conducted on this specific topic in order to have more precise and robust results.
Main subject category:
Health Sciences
Keywords:
Vitamin E, Vitamin C, Wound Healing, Ascorbic acid
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
74
Number of pages:
71
File:
File access is restricted only to the intranet of UoA.

ΔΙΠΛΩΜΑΤΙΚΗ ΕΡΓΑΣΙΑ ΛΕΠΙΔΟΥ ΣΟΝΙΑ-ΤΕΛΙΚΗ ΜΟΡΦΗ.pdf
1 MB
File access is restricted only to the intranet of UoA.