Use of medicinal cannabis in the treatment of symptoms of cancer patients

Postgraduate Thesis uoadl:3329086 41 Read counter

Unit:
Κατεύθυνση Ανάπτυξη Νέων Φαρμάκων: Έρευνα, Κυκλοφορία και Πρόσβαση
Library of the School of Health Sciences
Deposit date:
2023-05-25
Year:
2023
Author:
Chatzikyriakou Eleni
Supervisors info:
Κωνσταντίνος Ν. Συρίγος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Ανδριανή Χαρπίδου, Ακαδημαϊκή Υπότροφος, Ιατρική Σχολή, ΕΚΠΑ
Ηλίας Κοττέας, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Χρήση φαρμακευτικής κάνναβης στην αντιμετώπιση συμπτωμάτων ασθενών με καρκίνο
Languages:
Greek
Translated title:
Use of medicinal cannabis in the treatment of symptoms of cancer patients
Summary:
Cannabinoids, the active components of cannabis sativa (Cannabis sativa), mimic the effects of endogenous cannabinoids (endocannabinoids) by activating specific cannabinoid receptors, particularly the CB1 receptor found mainly in the central nervous system and the CB2 receptor found mainly in cells that involved with immune function. Delta-9-tetrahydrocannabinol (Delta-9-tetrahydrocannabinol), the main bioactive cannabinoid in the plant, has been made available as a prescription drug approved for the treatment of chemotherapy-induced nausea and vomiting as well as anorexia. Cannabinoids may be beneficial in the treatment of cancer pain since there may be a synergistic mechanism with opioid analgesics. Also, cannabinoids have been shown to be beneficial in the treatment of peripheral neuropathy from chemotherapy. Cannabinoids have a favorable drug safety profile, but their medical use is mainly limited by their psychoactive effects and limited bioavailability. The purpose of the study was to investigate the use of medicinal cannabis in the treatment of symptoms of cancer patients. A literature was conducted in the Google Scholar and Pubmed databases. The search was carried out without a chronological limitation and using the terms (individually and in combination): “cannabis”, “medicinal cannabis”, “cancer”, “cancer patients”, “symptoms, “management”
Main subject category:
Health Sciences
Keywords:
Cannabis, Medicinal cannabis, Cancer, Cancer patients, Symptoms, Management
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
81
Number of pages:
51
File:
File access is restricted only to the intranet of UoA.

ΔΙΠΛΩΜΑΤΙΚΗ ΕΡΓΑΣΙΑ ΧΑΤΖΗΚΥΡΙΑΚΟΥ ΕΛΕΝΗ.pdf
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