Faculty of Medicine
Library of the School of Health Sciences

2023-06-26

2023

Karabella Irena

Ισμήνη-Νίκη Δοντά, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπουσα
Ευστάθιος Χρονόπουλος, Καθηγητής, Ιατρική Σχολή ΕΚΠΑ
Γεώργιος Παναγιωτακόπουλος, Επίκουρος Καθηγητής, Ιατρική Σχολή, Πανεπιστήμιο Πατρών
Κασσή Ευανθία, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Μαυρογένης Ανδρέας, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Νικολάου Βασίλειος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Βασιλειάδης Ηλίας, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ

Φυματίωση των οστών - Πρόσφατα επιδημιολογικά δεδομένα

Greek

Bone tuberculosis - Recent epidemiological data

Tuberculosis (TB) is considered to be the greatest mimicker in medicine due to many different variations of clinical manifestations. Mycobacterium tuberculosis initially infects the lung and can be transmitted to any organ of human body. Involvement of bones and joints tuberculosis occurs in approximately 1-2 % of all TB cases.
The aim of this retrospective study was to assess the incidence of skeletal tuberculosis in Greece between 2011 and 2019, as the data for the prevalence in our country had been insufficient. In countries with low incidence of disease, the key to diagnosis is a high index of clinical suspicion. We identified 54 cases of bones and joints tuberculosis in “Sotiria” General Hospital – the National Center of Tuberculosis. The study showed that the majority of patients (81.5%) with skeletal tuberculosis were men whereas 18.5% were women. Among 54 cases of skeletal tuberculosis 79.6% were foreign-born individuals and 20.7% were born in Greece.
Frequently, the diagnosis of skeletal tuberculosis delays due to nonspecific symptoms and an atypical clinical picture. This serious condition can lead to neurological complications as well as skeletal damage. The gold standard of diagnosis is the needle aspiration biopsy or surgery biopsy both followed by a microbiological culture.
The treatment of bones’ and joints’ TB includes anti-tuberculosis agent chemotherapy however the optimal duration of treatment is an issue of extensive deliberations. In the current study patients that had received TB chemotherapy for less than 9 months were at 16.3 times higher risk of treatment failure or relapse versus patients that had received TB chemotherapy for more than 12 months.

Health Sciences

Bones and joints tuberculosis, Epidemiology, Immigration, Greek, Chemotherapy duration

No

0

Yes

362

177

File access is restricted until 2026-06-26.

https://pergamos.lib.uoa.gr/uoa/dl/object/3331901