Investigating the impact of vaccination on the length of hospitalization and the mortality of hospitalized patients with COVID-19 in a general hospital

Postgraduate Thesis uoadl:3392497 24 Read counter

Unit:
Κατεύθυνση Πρόληψη και έλεγχος Λοιμώξεων
Library of the School of Health Sciences
Deposit date:
2024-03-19
Year:
2024
Author:
Roussou Anna
Supervisors info:
Θεόδωρος Κατσούλας, Αναπληρωτής Καθηγητής, Τμήμα Νοσηλευτικής, ΕΚΠΑ, Επιβλέπων
Μαρία Τσερώνη, Επίκουρος Καθηγήτρια, Τμήμα Νοσηλευτικής, ΕΚΠΑ
Πέτρος Γαλάνης, Επίκουρος Καθηγητής, Τμήμα Νοσηλευτικής, ΕΚΠΑ
Original Title:
Διερεύνηση της επίδρασης της εμβολιαστικής κάλυψης στη διάρκεια νοσηλείας και στη θνητότητα νοσηλευόμενων ασθενών με COVID-19 λοίμωξη σε γενικό νοσοκομείο
Languages:
Greek
Translated title:
Investigating the impact of vaccination on the length of hospitalization and the mortality of hospitalized patients with COVID-19 in a general hospital
Summary:
Introduction: Vaccination is of great importance in the field of public health, being a preventive measure against a multitude of infectious diseases. The aim of the study is to investigate and evaluate how vaccination coverage affects mortality and length of stay in patients hospitalized for COVID-19 infection.
Methodology: The study was retrospective and analyzed the data of 3410 patients admitted to Piraeus Tzanio General Hospital with COVID-19 with or without vaccination from January 2020 to April 2023. Patient data collected included both demographics and clinical characteristics.
Results: Unvaccinated patients had a longer hospital stay, by almost 1 day, than vaccinated patients. Additionally, patients with comorbidities had a longer length of hospital stay, approximately 1.5 days, than patients who did not have an additional disease/disease. In addition, patients who received a mixture of COVID-19 vaccines had a longer length of hospital stay, approximately 1.5 to 3.5 days, than the other categories of the vaccine type variable. Intubation is associated with a significantly increased risk of death (Adjusted OR = 55.242 unadjusted and 90.427 with adjustment), indicating that intubated patients have a much higher risk of death. No statistically significant relationship was found between vaccination history and the likelihood of death. However, each additional vaccine dose appears to reduce the risk of death (Adjusted OR = 0.762).
Conclusions: In light of the above research findings, there is no doubt that vaccination is a powerful tool in the effort to control the COVID-19 pandemic. Studies conducted in developed and developing countries demonstrate that vaccination significantly reduces infection, severity of cases, and mortality from the virus.
Main subject category:
Health Sciences
Keywords:
Length of stay, Vaccination coverage, COVID-19, Mortality, Vaccines
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
158
Number of pages:
116
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